ID L8J5Z0_9CETA Unreviewed; 468 AA.
AC L8J5Z0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Pentraxin-4 {ECO:0000313|EMBL:ELR62872.1};
GN ORFNames=E5288_WYG008841 {ECO:0000313|EMBL:MXQ80854.1}, M91_08757
GN {ECO:0000313|EMBL:ELR62872.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR62872.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR62872.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YakQH1 {ECO:0000313|EMBL:ELR62872.1}, and yakQH1
RC {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
RN [2] {ECO:0000313|EMBL:MXQ80854.1, ECO:0000313|Proteomes:UP000322234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WY2019 {ECO:0000313|EMBL:MXQ80854.1};
RC TISSUE=Blood {ECO:0000313|EMBL:MXQ80854.1};
RA Liu Y.;
RT "The sequence and de novo assembly of the wild yak genome.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR EMBL; JH880269; ELR62872.1; -; Genomic_DNA.
DR EMBL; VBQZ03000005; MXQ80854.1; -; Genomic_DNA.
DR AlphaFoldDB; L8J5Z0; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR Proteomes; UP000322234; Unassembled WGS sequence.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR19277; PENTRAXIN; 1.
DR PANTHER; PTHR19277:SF122; PENTRAXIN-4; 1.
DR Pfam; PF00354; Pentaxin; 1.
DR PRINTS; PR00895; PENTAXIN.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..468
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036285110"
FT REGION 186..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 51020 MW; E8D96DA025240D0A CRC64;
MGSPTGRALP FFLILVHIYL HGALSQTTGP VGQRKPFFER LRRLEEQFRR FQEVTLTHLQ
GIASHYNLSF DIEARFQSLA HESRAVALAL NQSQVAVQDK LGHLRTWVRR TQRRGRKADH
RLLALSAAMS EGSARRAREQ ERQRAAVSGL ARDVRALQDA LLHLTPLVQS QSTRLAALEG
QLRLAGPGPA ARNVTPDPSR PSNPSAPQLQ GGGQTIRAPP EPRDPPLDFA YRLQGAQEPL
GLGNQQAWPP ESPGEVCNVG PALIFPNAST MNVGFLRPGF LTGLRALSIC SWVRTAADHL
GTLLSYATEE NDNKLVLHGR DSLAPGSVHF VIGDPAFREL PLQPLLDGQW HHVCVIWTSI
LGRYWLHVDR RLVATGSRFR EGYEIPPGGS LVLGQEQDHV GGGFDSSEAF VGSMAGLAIW
DRVLVPGEIS NLAMGKALPT GAILTLDNAT SVGGFVQRVN CTCLQLCP
//
