ID L8TP95_9MICC Unreviewed; 596 AA.
AC L8TP95;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Cell division protein FtsI/penicillin-binding protein 2 {ECO:0000313|EMBL:ELT43710.1};
GN ORFNames=G205_16729 {ECO:0000313|EMBL:ELT43710.1};
OS Arthrobacter nitrophenolicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=683150 {ECO:0000313|EMBL:ELT43710.1, ECO:0000313|Proteomes:UP000011189};
RN [1] {ECO:0000313|Proteomes:UP000011189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|Proteomes:UP000011189};
RX PubMed=23516196; DOI=10.1128/genomeA.00058-13;
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:e0005813-e0005813(2013).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELT43710.1}.
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DR EMBL; AOFD01000041; ELT43710.1; -; Genomic_DNA.
DR RefSeq; WP_009358616.1; NZ_AOFD01000041.1.
DR AlphaFoldDB; L8TP95; -.
DR PATRIC; fig|683150.5.peg.3281; -.
DR Proteomes; UP000011189; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:ELT43710.1};
KW Cell division {ECO:0000313|EMBL:ELT43710.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011189};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..222
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 268..572
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 596 AA; 63884 MW; AF91E9C5297BFE41 CRC64;
MAQRTGKPAD KVPNATRRLR LGLGIMLTLL LVVGGKLFLV QGLDVGGMAA AALDKRMTET
VLPAERGSIL DSNGTVLANS VIRYNVVVDQ RVNTKTETFK RLDEANEKLV DVSRDQGLTE
LAAALGMDKD AIREAVTGER PYYIVAKDVK PDVEDRISKL QIPGIVTEGV SKRVYPNGSV
AGGIIGFLKD GSTGQAGIEQ TQDELLRGKD GKRLFEIGAD GLRIPVGMDE LTPPQDGKDI
KLTINSDLQY FAQQAIQSQS DKLGAEWGSI IVMDAKTGDL VAMADTNAPD PNDPGRVAAK
DRGVRAVTAA YEPGSVQKMM TVAALIEEGK ASPLDTFTLG PSYTVDGQTF SDSFAHGTEE
RTLAGILGYS MNTGTVMAGQ RLSKQQRYEW LQKFGIGEAP DIGLPAEASG ILTPWEQWDG
RQEYTVLFGQ GVSQSTLQTV RAFQSIANNG VMLQPRLIDS YVSPDGAEEK VPAAPSRRIV
SEDTAEQVQD ILESAVTEGQ IKDAGIDGYR VGAKTGTSES PCDDGAGYCG YTASLVGMAP
MDDPRFIVEV VLQRPKGSIY GITNGPVFRS VMSQALRTYN VQPSTGEPAR LPQFAK
//
