ID L8WTP0_THACA Unreviewed; 1179 AA.
AC L8WTP0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Tubulin beta chain {ECO:0000313|EMBL:ELU41335.1};
GN ORFNames=AG1IA_04633 {ECO:0000313|EMBL:ELU41335.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU41335.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU41335.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- SUBUNIT: Dimer of alpha and beta chains. A typical microtubule is a
CC hollow water-filled tube with an outer diameter of 25 nm and an inner
CC diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to
CC form protofilaments running lengthwise along the microtubule wall with
CC the beta-tubulin subunit facing the microtubule plus end conferring a
CC structural polarity. Microtubules usually have 13 protofilaments but
CC different protofilament numbers can be found in some organisms and
CC specialized cells. {ECO:0000256|ARBA:ARBA00011747}.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU41335.1}.
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DR EMBL; AFRT01001079; ELU41335.1; -; Genomic_DNA.
DR AlphaFoldDB; L8WTP0; -.
DR STRING; 983506.L8WTP0; -.
DR HOGENOM; CLU_273216_0_0_1; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR CDD; cd02187; beta_tubulin; 1.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR Gene3D; 1.10.287.600; Helix hairpin bin; 1.
DR Gene3D; 3.30.1330.20; Tubulin/FtsZ, C-terminal domain; 1.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR InterPro; IPR013838; Beta-tubulin_BS.
DR InterPro; IPR002453; Beta_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR037103; Tubulin/FtsZ-like_C.
DR InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR023123; Tubulin_C.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF492; TUBULIN BETA-4 CHAIN; 1.
DR Pfam; PF01425; Amidase; 1.
DR Pfam; PF00091; Tubulin; 1.
DR Pfam; PF03953; Tubulin_C; 1.
DR PRINTS; PR01163; BETATUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SMART; SM00865; Tubulin_C; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
DR SUPFAM; SSF55307; Tubulin C-terminal domain-like; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
DR PROSITE; PS00227; TUBULIN; 1.
DR PROSITE; PS00228; TUBULIN_B_AUTOREG; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668}.
FT DOMAIN 46..244
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
FT DOMAIN 246..383
FT /note="Tubulin/FtsZ 2-layer sandwich"
FT /evidence="ECO:0000259|SMART:SM00865"
FT COILED 408..435
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1179 AA; 130347 MW; 0AC397BFECABE377 CRC64;
MREIVHLQTG QCGNQIGAKF WEVVSDEHGI AGDGKYQGNN DLQLECISVY YNTVGDNKYV
PRAVLVDLEP GTMDSVRSGP LGNLFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDAVLDVT
RKEAEGCDCL QGFQITHSLG GGTGAGMGTL LISKIREEYP DRMMCTFSVV PSPKVSDTVV
EPYNATLSVH QLVENSDETF CIDNEALYDI CFRTLKLSTP TYGDLNHLVS IVMSGVTTCL
RFPGQLNSDL RKLAVNMVPF PRLHFFMVGF APLTARGSVQ YRAVSVPELT QQMFDAKNMM
AASDPRHGRY LTVAAFFRGK VSMKEVEEQM QNVQNKNSAY FVEWIPNNVL TAQCDIPPRG
MKMAATFIGN STAIQELFKR VSEQFSAMFK RKAFLHWYTQ EGMDEMEFTE AESNMQDLVA
EYQQYQDASV EEEGEYEEDV PAEEQLSVPD YSWVSDKHMV WAFYVTTLSM TELRVYKAVV
SVALDKPSLP QIRPTQEGKA HEIYIAQIRV RVLCRYRHHS LGVGKRKGRR LSSTLWNNIK
EVMEVASVVS LIYRQAEQLK RIWPIARGPA FFFVRPTPIT SSGSLLRSTC TICIAPFYSS
GVLYVRCHEW TRWLKSDNDV NAMRLSRLVL FSSLLSNVWA RRLDEIDLYE VSIAELQAGL
ESRSFTAVDL VKAYLGRINQ VNHAGPKLNA IIETNKHALH QARELDEERK VFGKRSPLHG
IPILVKDSIS TLASEDTRIG MNTTAGSYAL FGSVVREEAT VVAKLRKAGA IILGKANMCE
WSYARGDLTN GWSGRGGQTT SPFYPGSDPC TSSGGSAVAA TLGLAAASLG VETRGSIICP
SSYNNLVGLK PTVGLTSRAG GVFLAFGEPE YRADGSSYQS VADAATILNI IAGQDERDNF
TSTAPSLIPD YTKYLDPNAI RGKRFGVPRK GLTNETMAGT HPSVNIEFGK ALDKIRELGG
VVIDPADLPS AEEIPHRHET WAAMVQFKIL LRDYIRNLVH VPTNVTCVAD VIAFNNAHKD
LERPEGLELA ETTEGFNSTY FDALHQNHMI GRERGIDAAL KTHGLDALLL PTNMHTAVPA
GLAGYPVITV PLGFHPEGTK PNPDTRGQHK VLYPAPGMPF GLSFIGTAYT EQSLIGFAYA
YEQYTHTRLQ RRAYSEAIPT VQLKDVVGIS EEDTIVFQS
//
