ID L8WYJ1_THACA Unreviewed; 197 AA.
AC L8WYJ1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=AG1IA_04525 {ECO:0000313|EMBL:ELU41434.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU41434.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU41434.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- SIMILARITY: Belongs to the peptidase C56 family. HSP31-like subfamily.
CC {ECO:0000256|ARBA:ARBA00038493}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU41434.1}.
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DR EMBL; AFRT01001056; ELU41434.1; -; Genomic_DNA.
DR AlphaFoldDB; L8WYJ1; -.
DR STRING; 983506.L8WYJ1; -.
DR HOGENOM; CLU_070319_2_0_1; -.
DR OMA; GEKTGFW; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0019172; F:glyoxalase III activity; IEA:UniProt.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 26..161
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 197 AA; 21347 MW; 2C4BF049434B349D CRC64;
MPSVLFVFTS ANKTLTGAQT GWYLPEAAHP YYVLHEKINI DFAAPNGPNP EVDEGSVEMF
KDDESVKFLQ DPEVKQKFAS AKKLSDVNPA EYDAIFYVGG HGPMIDLPED PNNIKLANAF
YQSGKITSAV CHGPGALVGV TDASGKSIFD GRNATGFSDA EEEQVGKVKD VPFLLETRIK
ELGGKYTKAE QAWGVSN
//
