ID L9KIH6_TUPCH Unreviewed; 856 AA.
AC L9KIH6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Protein PML {ECO:0000313|EMBL:ELW62488.1};
GN ORFNames=TREES_T100010856 {ECO:0000313|EMBL:ELW62488.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW62488.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB320813; ELW62488.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KIH6; -.
DR STRING; 246437.L9KIH6; -.
DR eggNOG; KOG2177; Eukaryota.
DR InParanoid; L9KIH6; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19804; Bbox1_TRIM19_C-V; 1.
DR CDD; cd19770; Bbox2_TRIM19_C-V; 1.
DR CDD; cd16579; RING-HC_PML_C-V; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR021978; PML-like_CC.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF301; PROTEIN PML; 1.
DR Pfam; PF12126; DUF3583; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 32..66
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 101..143
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 161..210
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 94454 MW; 252477316FDB4ED1 CRC64;
MSPPNSPPED HEPGPSHSPA EQGAEEFQFL RCQACKAEAK CPKLLSCLHT LCSRCLEERG
MQCPICCVLE TPGSGAAVPA LNNTFFESLQ GRLSVYRQIV DAQALCTRCK EAADFWCFEC
EHLLCAKCFE AHQWFLKHEA QRLAELRSQS VCEFLDGTRK SNNIYCSNPN HRTPALTSIY
CRGCSKPLCC SCALLDSGHG DLMSDISTEI QQRQSELDGM THALREQDGA FGAAHAQVHA
AIDQLDQARR DTEELIRQGV RQLLAHVQAQ ERELLQAVEA RYHRDRRELD SRMGRLDTVL
QRIRTGSTLV ERMKRYASDQ EVLDMHSFLR QALCSLRQEE PQSLQAPVCT DGFKEFKARL
QSLSSCVMEG KDAAPSRRAS PEAASTPRDP IDIDPPEKVQ RVQAQGQGPA EAQSVAVVQP
VPGAHPVPVF AFSIKEPSCG EISHTTTSQK RKSCQTQSPR KVIKMESEEE REARLARSPS
VQPRPSTSKA VSPFRLDGPT SPGHPTVGDE VSLPSSNHLA STAGEEAEER IVVISSSEDS
DVDNPCSQEP EDSSSEASDL QLEGPDSFRV LDESLADPQE EDRPLVFFDI KIDNETQKIS
QLAAVSRESR FRVLIHTEAF GVHSKAVSLE TGLQHFLGFL GAMHCPILAC YKLWGPGLPN
FFQALEDMNR LWEFREAVSG FLAVLPLIRE RVPGASSFQL KSLAKTYLAR NVSERSALAA
VLAMRDLCRL LEVSPGPQLA LHVYPVTSLQ CFASLQPLVR AAVLLRAQAR LLALHNVSFR
ELLAAHRRDP QGGLKRYCRY LSLQTTLPFP AQPAIPLQAL GTYFEGLSER LALARAEGSS
VPPAAHSSAE EASQQS
//
