ID L9KRI5_TUPCH Unreviewed; 1037 AA.
AC L9KRI5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=WD repeat-containing protein 47 {ECO:0000313|EMBL:ELW65333.1};
GN ORFNames=TREES_T100013984 {ECO:0000313|EMBL:ELW65333.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW65333.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320697; ELW65333.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KRI5; -.
DR STRING; 246437.L9KRI5; -.
DR eggNOG; KOG0641; Eukaryota.
DR InParanoid; L9KRI5; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040067; WDR47.
DR PANTHER; PTHR19863; NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG; 1.
DR PANTHER; PTHR19863:SF5; WD REPEAT-CONTAINING PROTEIN 47; 1.
DR Pfam; PF17814; LisH_TPL; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..219
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT REPEAT 775..805
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 869..909
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 914..955
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 956..990
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1002..1037
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 510..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1037 AA; 115086 MW; BA1DFAA240DE3CE0 CRC64;
MKRRTRLPER AVRSPAAGFL PRRRLPSSFL LRRFSGLAPE PPGAQKLNCC GGSSGKAFIQ
TAGKGTRLTV NAFYIILFTG HFHLVFIDLI HAKPIEKPVG QQLASTICCN IICQAINMTA
EETVNVKEVE IIKLILDFLN SKKLHISMLA LEKESGVING LFSDDMLFLR QLILDGQWDE
VLQFIQPLEC MEKFDKKRFR YIILKQKFLE ALCVNNAMSA EDEPQHLEFT MQEAVQCLHA
LEEYCPSKDD YSKLCLLLTL PRLTNHAEFK DWNPSTARVH CFEEACVMVA EFIPADRKLS
EAGFKASNNR LFQLVMKGLL YECCVEFCQS KATGEEITES EVLLGIDLLC GNGCDDLDLS
LLSWLQNLPS SVFSCAFEQK MLNIHVDKLL KPTKAAYADL LTPLISKLSP YPSSPMRRPQ
SADAYMTRSL NPALDGLTCG LTSHDKRISD LGNKTSPMSH SFANFHYPGV QNLSRSLMLE
NTECHSIYEE SPERSDTPVE AQRPISNEVL GQSSVSEKEP ANGAQNPGPP KQEKNELRDS
TEQFQEYYRQ RLRYQQHLEQ KEQQRQIYQQ MLLEGGVNQE DGPDQQQNLT EQFLNRSIQK
LGELNIGMDS LGNEVSALNQ QCNGSKSNGS NNSSMTSFAT PPQDSSQRSA HDTSTVHTST
PRNPGTTNHI PFLEESPCGS QISSEHSVIK PPLGESPGNL SRSRGEEDDK SKKQFVCINT
LEDTQAVRAV AFHPSGGLYA VGSNSKTLRV CAYPEVIDPS AHDTPKQPVV RFKRNKHHKG
SIYCVAWSPC GQLLATGSND KYVKVLPFNA ETCNATGPDL EFSMHDGTIR DLAFMEGPES
GGAILISAGA GDCNIYTTDC QRGQGLHALS GHTGHILALY TWSGWMIASG SQDKTVRFWD
LRVPSCVRVV GTTFHGTGSA VASVAVDPSG RLLATGQEDS SCMLYDIRGG RMVQSYHPHS
SDVRSVRFSP GAHYLLTGSY DMKIKVTDLQ GDLTKQLPIM VVGEHKDKVI QCRWHTQDLS
FLSSSADRTV TLWTYNG
//
