ID   L9WL74_9EURY            Unreviewed;      1165 AA.
AC   L9WL74;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Helicase HerA central domain-containing protein {ECO:0000259|Pfam:PF01935};
GN   ORFNames=C494_08817 {ECO:0000313|EMBL:ELY49088.1};
OS   Natronorubrum bangense JCM 10635.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natronorubrum.
OX   NCBI_TaxID=1227500 {ECO:0000313|EMBL:ELY49088.1, ECO:0000313|Proteomes:UP000011690};
RN   [1] {ECO:0000313|EMBL:ELY49088.1, ECO:0000313|Proteomes:UP000011690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10635 {ECO:0000313|EMBL:ELY49088.1,
RC   ECO:0000313|Proteomes:UP000011690};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELY49088.1}.
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DR   EMBL; AOHY01000023; ELY49088.1; -; Genomic_DNA.
DR   AlphaFoldDB; L9WL74; -.
DR   STRING; 1227500.C494_08817; -.
DR   PATRIC; fig|1227500.6.peg.1769; -.
DR   eggNOG; arCOG04816; Archaea.
DR   Proteomes; UP000011690; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR30121:SF6; TYPE IV SECRETION SYSTEM PROTEIN CAGE; 1.
DR   PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          382..593
FT                   /note="Helicase HerA central"
FT                   /evidence="ECO:0000259|Pfam:PF01935"
FT   REGION          66..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          335..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          767..925
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..350
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        796..811
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        842..869
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1165 AA;  130658 MW;  502C1C6A233AD182 CRC64;
     MDTAPPTFEF LAVSAGPDAP VEFYYGVNQG EHLNTLEKRL RSIYPTTFTV ARTELNLELM
     LGLQTEVSNE DTSEQAMQDT LDGERSADLD ESNPEGTDEK NVDDECIEHT PFGVEWLGKV
     GRKTDWMTTI TPFVIDEPDE EYDSDQPPLS AVVEVLHEMT APTVYQILWQ RKPDWRDDAE
     IRQSNLKEGR DTWSEELIGS WFEPVDADPA DRELSRETED LIQRIDSKHP RRTFTVNARA
     VAMARPDETE IRAELDQLKA SLDPLDGPFY ELFGRRVREK GFLDRQKAKR AQRHLDRVLN
     GEMITGSGKK RPDFVFNADE LANVVVVPSA DNLTVEGSRG ARSEQRSRSP LPRPNPDLMA
     QFREGMAIGY ALDKNKIIQP DSIRIPPNLL TRHYGRFAST GAGKSKAIIN DALSLRETTG
     GPVIIVDPKG DGMCANYLRC HYERFSGLDN TYQFYVPDTL PAFSFFDIRS TLEAGWRRED
     AIQDKVDHFH DIMRMVMGRK QYEQAFVANE ILSYLIKALF DEEYGNDAFG LDDLFAAALQ
     MQRERTIPPV AAENQNVEES LTRHFEKDDR QFQVSMDAVG NRLDKLREDA HLRRIFSHVP
     QQGDDGEYVD NRFDFREFLD EDVTILFDLG DLRPEAQRAI TLLLLSNLWD AVRVRRRDGK
     TDYENLTNLI IEEAAPVAST KLVSEQLLPQ GRSFGLSMGL VMQFPGQVRN RSERAYDEVL
     NNIKTKLIGN ISIERDLAES LAHEDLSPTD LRNRVNTLPS GEWIAQLPSP SFGETGPAPF
     SVKPLPIASG HPESDKPLSV EQEDHFETVA LPRLSERTQS QYGLAEASAE SEAADNEGWG
     SRPNGARSTS AESASPVDST QSSFIGQATS GLAADEEGQK EAGTTNLLFG DPESTASEEP
     AAEAEETTVD ENESSPLQSP VQAGGVTVPD DVLRQRGLTH DDVRFLTRIL DVMNGDDPDH
     TLLDSMSAFK NDFDDLDVQR LVDQDLLEEE RACGRKYYTV LPAGRELLGQ KLKVGPGQGD
     IGEKTPHKVG VKLLELWLEA RDDVEKVEPY YEYDEETVFD VAGLDTDGEL VWVGEAELAS
     NNKHAPVDDY DKQSRVDANV VWAFNRRETA VEVLDHLAEA DRIECSVSGR AARSFSDIRE
     AVESFDATGL TTIRSFNKLD QEFNT
//