ID L9XAP2_9EURY Unreviewed; 444 AA.
AC L9XAP2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Potassium transporter peripheral membrane component {ECO:0000313|EMBL:ELY58486.1};
GN Name=trkA {ECO:0000313|EMBL:ELY58486.1};
GN ORFNames=C492_11735 {ECO:0000313|EMBL:ELY58486.1};
OS Natronococcus jeotgali DSM 18795.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=1227498 {ECO:0000313|EMBL:ELY58486.1, ECO:0000313|Proteomes:UP000011531};
RN [1] {ECO:0000313|EMBL:ELY58486.1, ECO:0000313|Proteomes:UP000011531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18795 {ECO:0000313|EMBL:ELY58486.1,
RC ECO:0000313|Proteomes:UP000011531};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY58486.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOIA01000114; ELY58486.1; -; Genomic_DNA.
DR RefSeq; WP_008423612.1; NZ_AOIA01000114.1.
DR AlphaFoldDB; L9XAP2; -.
DR STRING; 1227498.C492_11735; -.
DR PATRIC; fig|1227498.3.peg.2275; -.
DR OrthoDB; 27588at2157; -.
DR Proteomes; UP000011531; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 2..127
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 139..220
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 228..351
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 363..444
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 444 AA; 48106 MW; E96F45C4DEE2DB92 CRC64;
MRVIIVGAGE VGRSIAQNLQ ASHEVVVVDR DEEIVEDLTY SMDVLAIRGN GTEIGTLREA
GIEDADLVIA STDNDESNVV ICGAAKTKSD AFTIARVRRR TLLETWQGSQ GAFGVDFMVC
TDLLTAQTIF RISGLPAAQD VNMFAGGLVR MAEFEIGGDS PVADRSVQEA DCYDSMTFAA
IFRDDEMIVA SGESIIRPGD RVVVIGSPDS VKGFASDITS PGQDEDKEIV IIGASEIGFQ
TAREFEDHGY KPRLIERDHE RAREVAEALP NTIVMESDAT DTEFLVREHV DEADLVVATL
DGDEKNLLAS LLAKRLGVDR TIGVIENHQY ADLFEQVGVD VAINPREETA EEIIRFTHAD
HTEKIAMVEH DRAEVIEIEV GEDSVLTNRS IAEATADLPE CVVIGAISRG GELITPRGTT
VVEPGDHVVL FVDAAVLDQV LEGL
//
