ID   L9YTZ0_9EURY            Unreviewed;       266 AA.
AC   L9YTZ0;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Translation initiation factor IF-2 subunit alpha {ECO:0000313|EMBL:ELY77589.1};
GN   ORFNames=C486_15834 {ECO:0000313|EMBL:ELY77589.1};
OS   Natrinema gari JCM 14663.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrinema.
OX   NCBI_TaxID=1230459 {ECO:0000313|EMBL:ELY77589.1, ECO:0000313|Proteomes:UP000011592};
RN   [1] {ECO:0000313|EMBL:ELY77589.1, ECO:0000313|Proteomes:UP000011592}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 14663 {ECO:0000313|EMBL:ELY77589.1,
RC   ECO:0000313|Proteomes:UP000011592};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- SIMILARITY: Belongs to the eIF-2-alpha family.
CC       {ECO:0000256|ARBA:ARBA00007223}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELY77589.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOIJ01000061; ELY77589.1; -; Genomic_DNA.
DR   RefSeq; WP_008457570.1; NZ_AOIJ01000061.1.
DR   AlphaFoldDB; L9YTZ0; -.
DR   GeneID; 13349768; -.
DR   PATRIC; fig|1230459.4.peg.3159; -.
DR   Proteomes; UP000011592; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd04452; S1_IF2_alpha; 1.
DR   Gene3D; 3.30.70.1130; EIF_2_alpha; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR003029; S1_domain.
DR   InterPro; IPR044126; S1_IF2_alpha.
DR   InterPro; IPR024055; TIF2_asu_C.
DR   InterPro; IPR024054; TIF2_asu_middle_sf.
DR   InterPro; IPR011488; TIF_2_asu.
DR   PANTHER; PTHR10602; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR   PANTHER; PTHR10602:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR   Pfam; PF07541; EIF_2_alpha; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF110993; eIF-2-alpha, C-terminal domain; 1.
DR   SUPFAM; SSF116742; eIF2alpha middle domain-like; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50126; S1; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW   ECO:0000313|EMBL:ELY77589.1};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT   DOMAIN          10..81
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
SQ   SEQUENCE   266 AA;  29566 MW;  7A971F4021D04C77 CRC64;
     MKYSGWPDPG ELVVGKIDEI EDFGVFVDLE EYEDKRGLIH ISEVASGWIK NVRDHVREGQ
     IVVCKVLDVD EGSQQIDLSL KDVNDHQRSD KIQEWKNEQK ADNWMELAFG EEIADEDYTA
     IANDLIAIHG GLYEGFKQAA IHGTEALDDT DLDDDEIASI VETARENVSV PYVNVTGYVD
     LENPTETGVD GIREALEAAE GNGEVPEEVD LEVSYVGAPE YRITVRAPNY KTAESQLEDS
     AQRAVAAIEG HGGAGEYHRE RRTDDE
//