ID LYTR_STRA3 Reviewed; 246 AA.
AC Q8E7H3;
DT 15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Sensory transduction protein LytR;
GN Name=lytR; OrderedLocusNames=gbs0181;
OS Streptococcus agalactiae serotype III (strain NEM316).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=211110;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEM316;
RX PubMed=12354221; DOI=10.1046/j.1365-2958.2002.03126.x;
RA Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T.,
RA Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F.;
RT "Genome sequence of Streptococcus agalactiae, a pathogen causing invasive
RT neonatal disease.";
RL Mol. Microbiol. 45:1499-1513(2002).
CC -!- FUNCTION: Member of the two-component regulatory system LytR/LytS that
CC probably regulates genes involved in cell wall metabolism.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- PTM: Phosphorylated by LytS. {ECO:0000250}.
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DR EMBL; AL766844; CAD45826.1; -; Genomic_DNA.
DR RefSeq; WP_000697630.1; NC_004368.1.
DR AlphaFoldDB; Q8E7H3; -.
DR SMR; Q8E7H3; -.
DR KEGG; san:gbs0181; -.
DR eggNOG; COG3279; Bacteria.
DR HOGENOM; CLU_000445_14_1_9; -.
DR Proteomes; UP000000823; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR CDD; cd17532; REC_LytTR_AlgR-like; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR046947; LytR-like.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR37299:SF1; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04397; LytTR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00850; LytTR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..246
FT /note="Sensory transduction protein LytR"
FT /id="PRO_0000081135"
FT DOMAIN 2..118
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 142..246
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00112"
FT MOD_RES 55
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 246 AA; 28145 MW; 1F21191228CE2554 CRC64;
MKILILDDEM FARQELSFLV EHSQEVDNPE IFQAEDISEA EKILFRQQID LIFLDISLSE
ENGFTLANQL SQLAHPPLVV FATAYDNYAV KAFESNAVDY IMKPFEQQRV DMALSKVKKL
SQLTTASDVE QAIPKKASVE LLTLTLSDRS VVVKMQDIVA ASVEDGELTV STVQKTYTIR
KTLNWFKSRA VAPYFLQIHR NTVINLEMIE EIQPWFNHTL LLIMSNGEKF PVGRSYLKDL
NEHLTM
//
