ID M0A8S6_9EURY Unreviewed; 265 AA.
AC M0A8S6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:ELY94771.1};
GN ORFNames=C484_05462 {ECO:0000313|EMBL:ELY94771.1};
OS Natrialba taiwanensis DSM 12281.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrialba.
OX NCBI_TaxID=1230458 {ECO:0000313|EMBL:ELY94771.1, ECO:0000313|Proteomes:UP000011648};
RN [1] {ECO:0000313|EMBL:ELY94771.1, ECO:0000313|Proteomes:UP000011648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12281 {ECO:0000313|EMBL:ELY94771.1,
RC ECO:0000313|Proteomes:UP000011648};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY94771.1}.
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DR EMBL; AOIL01000016; ELY94771.1; -; Genomic_DNA.
DR RefSeq; WP_006824928.1; NZ_AOIL01000016.1.
DR AlphaFoldDB; M0A8S6; -.
DR PATRIC; fig|1230458.4.peg.1104; -.
DR OrthoDB; 14763at2157; -.
DR Proteomes; UP000011648; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF35; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..69
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 70..253
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 265 AA; 29163 MW; ABCCAB8263A8CA86 CRC64;
MADRNDNDAI QTTNTSFEII HALQELGPAR LSTIADRLGL AESTTHRHLQ TLSDLRYVSR
DGDRYQIGLR FARLGRAAQT RDPAYEMAKP HVQELAEETG ERAQFVVEDH GLGIYLHVET
GSRAVRVGFG VGRQIHLHSS SAGKAILAHS PRERVDDILD QWGLPAHATN TITDRDALYD
ELETVRERGV AFNREEHVDG LNGTAVPVKR DGRAVGALAV AGPSHRLTGE WFEDEVPSMM
LAAANELELN VTYASDASST DHIVE
//
