ID M0C077_9EURY Unreviewed; 448 AA.
AC M0C077;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN ORFNames=C476_17967 {ECO:0000313|EMBL:ELZ15339.1};
OS Natrinema limicola JCM 13563.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1230457 {ECO:0000313|EMBL:ELZ15339.1, ECO:0000313|Proteomes:UP000011615};
RN [1] {ECO:0000313|EMBL:ELZ15339.1, ECO:0000313|Proteomes:UP000011615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13563 {ECO:0000313|EMBL:ELZ15339.1,
RC ECO:0000313|Proteomes:UP000011615};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ15339.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOIT01000092; ELZ15339.1; -; Genomic_DNA.
DR RefSeq; WP_008015506.1; NZ_AOIT01000092.1.
DR AlphaFoldDB; M0C077; -.
DR STRING; 1230457.C476_17967; -.
DR PATRIC; fig|1230457.4.peg.3546; -.
DR eggNOG; arCOG00471; Archaea.
DR OrthoDB; 195574at2157; -.
DR Proteomes; UP000011615; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Cell cycle {ECO:0000313|EMBL:ELZ15339.1};
KW Cell division {ECO:0000313|EMBL:ELZ15339.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000011615}.
FT DOMAIN 66..238
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT BINDING 78..82
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 237
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 249
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 448 AA; 50233 MW; 34B99FBF41A2C2BF CRC64;
MSDGDEQQSL SQSIKGRLQE GVQNSVFKDK GLLDPDTVID EDRIVGRDQQ LDDIITYLRP
ALQGNRPPNM LLYGPSGTGK SLIINAVCQQ VQELANAQGD RFGVIRVNCQ TIKSHDRAVY
RLVESAAIGV GVDPGVPESG VSTDQKLNRF YEILSENFDS VIIILDEVDL LVGRQRDPND
EPAYSKLLYQ LSRASQLGRI EGDVSVAALT NDPRFMENLD GRAESSFNPQ DIVFPDYDAN
QLQAILGRRR DAYRDNVLED GIIPLSSAYA AQDHGDARKA IDLFRKAGEI ADRQGEDRVR
EEHVRGAQKE AERDRTLTQM QGLSTQKKLS LYATAIVPVY SQRNLNAVPS TVAYRVYQYI
TDILDTDEKS RDSYLRYMSE AETYNFVTSD KRGRGYGSGV HKEYTFVDDP EVVAETLQSD
IRLEEIENDE DLIRSVVNAQ IDDFFDGK
//
