ID   M0D3Q3_9EURY            Unreviewed;       341 AA.
AC   M0D3Q3;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Adaptive-response sensory-kinase {ECO:0000313|EMBL:ELZ29327.1};
GN   ORFNames=C475_03884 {ECO:0000313|EMBL:ELZ29327.1};
OS   Halosimplex carlsbadense 2-9-1.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Halosimplex.
OX   NCBI_TaxID=797114 {ECO:0000313|EMBL:ELZ29327.1, ECO:0000313|Proteomes:UP000011626};
RN   [1] {ECO:0000313|EMBL:ELZ29327.1, ECO:0000313|Proteomes:UP000011626}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2-9-1 {ECO:0000313|EMBL:ELZ29327.1,
RC   ECO:0000313|Proteomes:UP000011626};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ29327.1}.
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DR   EMBL; AOIU01000008; ELZ29327.1; -; Genomic_DNA.
DR   RefSeq; WP_006882449.1; NZ_AOIU01000008.1.
DR   AlphaFoldDB; M0D3Q3; -.
DR   STRING; 797114.C475_03884; -.
DR   PATRIC; fig|797114.5.peg.789; -.
DR   eggNOG; arCOG02366; Archaea.
DR   OrthoDB; 327291at2157; -.
DR   Proteomes; UP000011626; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR   PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ELZ29327.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011626};
KW   Transferase {ECO:0000313|EMBL:ELZ29327.1}.
FT   DOMAIN          6..67
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          136..339
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   341 AA;  37051 MW;  7A76ACAF9C4BDAA8 CRC64;
     MSGQRSAERF DALFELIDDA VVEVEIVEMR PVVRAVNPGF ESVFGWSAET VVGESLNDFI
     VPEGRAEAAV DFDQRTADGK VNSGTVTRRT ADGLRQFIYR GVPYEHGDGG RGGLAIYTDI
     TERTRRKRHH AVVHRVLRHN LRNALTVILG SVNEVERMTD GPVAEQARLA RSAARDLETL
     SERARLVERA FDEEINRQVV DVADLFRSVA SAVRSVNGSA TVTTELPGRL PVLAGGPLEA
     ALENLVSNAV IHGGDAPDVR VVGRRAGDTV EIDVVDDGPG IPDGVRAVVF ADRPLTQLSH
     STGLGLWLAK WAIEACHGRL DYRRVDGETV VRVTLPAVDE A
//