ID M0DX16_9EURY Unreviewed; 832 AA.
AC M0DX16;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=C463_15977 {ECO:0000313|EMBL:ELZ40016.1};
OS Halorubrum californiense DSM 19288.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1227465 {ECO:0000313|EMBL:ELZ40016.1, ECO:0000313|Proteomes:UP000011586};
RN [1] {ECO:0000313|EMBL:ELZ40016.1, ECO:0000313|Proteomes:UP000011586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19288 {ECO:0000313|EMBL:ELZ40016.1,
RC ECO:0000313|Proteomes:UP000011586};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ40016.1}.
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DR EMBL; AOJK01000073; ELZ40016.1; -; Genomic_DNA.
DR RefSeq; WP_008445624.1; NZ_AOJK01000073.1.
DR AlphaFoldDB; M0DX16; -.
DR STRING; 1227465.C463_15977; -.
DR PATRIC; fig|1227465.4.peg.3092; -.
DR OrthoDB; 42357at2157; -.
DR Proteomes; UP000011586; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 750..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..808
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..388
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 643..807
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 832 AA; 88721 MW; 97738EA0F0801A98 CRC64;
MTAADRLIEE IDRVVTERPL AVIAVFLLVT VVFAGGLTGI ETSAGADQFT QDIPAQQALD
NIDEEFETSI GGSPTSAQVI VSDDNVLSRD ALVRTLETQH RLESRSTLRV ASTSSHADAI
ARQLDPDAAN AAERRDAVAE ATPAELRTAI ADADATGAIA AQVSVDYNPT AQAADTAIVG
ITYDLPDAAT TTRVTELQTR SVDVVDSVPG NVAGENAILF GDGVLQSEIT ALLTDTAIIV
FPAALILIVG FLIFSYRDPF DMAIGIGALL LSLLWTFGFM GYAGIPFSDS LVTVFPLLLA
VGIDFGIHIV NRYREERATG TGIEESMRTT TDQLLIAFLL VTITTVFSLV SNVVSPFDPN
RDFGIVAAVG ITFTLVIFGV FLPAAKVLSD RWRKRLPIPE FGTSALGAGG SRIARVLHVG
VDLSRIAPVA VVALLLVGGA VGGAYGTGVN TEFSEEAFFP DQDRLETYAN LPEPFAPTEY
TFLDVLNIFE DEFEQSFVGS VTLYVDQSVR DDDALELIDR TTRNPPATFA TTDKRRAQAT
SVVTVIEDRA ERDPEFAALV ERNDRLGNGV PDRNVDEVYD ALLDSSAEGQ ARGYVAADRG
SARIDYTIRP GVDNSEAVAD VRDLAERTPL EAVPTGSLVV NEAVIDLLTE SAIRSLFAAF
GLTALFLALS YAYLEGKAVY GLLNLVPVLV TVGLLVGSMR LFEIPLTPIN APILSVSIGL
GVDYTVHFVH RFVDEYQEGL PIDEALDVTI AGTGGALTGS MLTTVSGLGV LWLAVIPLLR
DFGVLLALGV FYAYLCSILL VPSLVVVWDR YAGLVGLGLD DGLRESGAES GR
//
