ID M0FEP7_9EURY Unreviewed; 461 AA.
AC M0FEP7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=C460_09527 {ECO:0000313|EMBL:ELZ58415.1};
OS Haloferax sp. ATCC BAA-646.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=1227464 {ECO:0000313|EMBL:ELZ58415.1, ECO:0000313|Proteomes:UP000011677};
RN [1] {ECO:0000313|Proteomes:UP000011677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-646 {ECO:0000313|Proteomes:UP000011677};
RA Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA Eisen J.A., Facciotti M.T.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELZ58415.1, ECO:0000313|Proteomes:UP000011677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-646 {ECO:0000313|EMBL:ELZ58415.1,
RC ECO:0000313|Proteomes:UP000011677};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ58415.1}.
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DR EMBL; AOLD01000030; ELZ58415.1; -; Genomic_DNA.
DR AlphaFoldDB; M0FEP7; -.
DR PATRIC; fig|1227464.4.peg.1889; -.
DR Proteomes; UP000011677; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR030665; KaiC.
DR InterPro; IPR014774; KaiC-like_dom.
DR InterPro; IPR010624; KaiC_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42926; -; 1.
DR PANTHER; PTHR42926:SF1; KAIC-LIKE PROTEIN 2; 1.
DR Pfam; PF06745; ATPase; 2.
DR PIRSF; PIRSF039117; KaiC; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51146; KAIC; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..218
FT /note="KaiC"
FT /evidence="ECO:0000259|PROSITE:PS51146"
FT DOMAIN 220..454
FT /note="KaiC"
FT /evidence="ECO:0000259|PROSITE:PS51146"
SQ SEQUENCE 461 AA; 50458 MW; 2EBC66B7F05EB061 CRC64;
MPNRTYMVRG ESGAGKTIAG YHFLTAGREN DEDVLFISFE ESNADLRANA GTLGFDLSEV
PILDLSPSPE AFLDDEAYTM LSPGEVEGRS TTTELKEAIE EHDPDRVVID PLSQLGRLSS
DGYQFRRLVS SLLSYLKRSG ATTLFTSQPS SGGTDETLAY LCDGSISLSR SDWGRSVRIE
KFRGSDSQTG PHAMRIDGGH GMRVFPRLVP DSHHREFTIE PLSSGIDDLD TLLGGGIERG
SITLVSGPSG VGKSTTGAAF ARATAERGER AAIYLFEESK RSFRHRSESV GIPIDDLVEA
GDLRVDAVEP LSLSTDEFAQ RVRAEVEAND TKFVLIDGTA GYQLSLTDER SDIRRELHAL
ARYLKNMGVT VVLTEEVQQV TGAFHASDNH VSYLADNILF IRYIEVRGEI RKAVGVLKKR
FGGFEPTLRS FEIGRDGITV GEPLDELRGI LTGTPTWNEA E
//
