ID M0FWB8_9EURY Unreviewed; 274 AA.
AC M0FWB8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:ELZ64366.1};
GN ORFNames=C459_07545 {ECO:0000313|EMBL:ELZ64366.1};
OS Haloferax sp. ATCC BAA-645.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=1227463 {ECO:0000313|EMBL:ELZ64366.1, ECO:0000313|Proteomes:UP000011673};
RN [1] {ECO:0000313|EMBL:ELZ64366.1, ECO:0000313|Proteomes:UP000011673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-645 {ECO:0000313|EMBL:ELZ64366.1,
RC ECO:0000313|Proteomes:UP000011673};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ64366.1}.
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DR EMBL; AOLE01000019; ELZ64366.1; -; Genomic_DNA.
DR RefSeq; WP_008574022.1; NZ_AOLE01000019.1.
DR AlphaFoldDB; M0FWB8; -.
DR PATRIC; fig|1227463.4.peg.1519; -.
DR Proteomes; UP000011673; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046826; PDH_N.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 26..115
FT /note="Prephenate dehydrogenase nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02153"
FT REGION 243..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 28081 MW; BB8EB8CEB34A7F49 CRC64;
MDVLIVGAGA MGRWFGRTVD ADLAFADADP ESAVAAADAL GGRAVPLDGD ERFDVVCLAV
PMRLAADAVA GNAHRTDAAM CDVTGAMGPP VAAMRDHLPD RERLSLHPLF APHNAPGNVA
AVTDEPGAYT DALLSGLDAA GNRVFETTPE EHDAAMETVQ AAAHAAVLAF GLAADDVREE
FATPISAALD ELVASVSGGT PRVYADIQSS FGGGADRVAD AARELAAADD EAFADLYRRV
SRGDDAGVGS AGDAGDASAD DRTRDQTDKH DPVE
//
