ID M0I7W2_9EURY Unreviewed; 445 AA.
AC M0I7W2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Potassium transporter peripheral membrane component {ECO:0000313|EMBL:ELZ92082.1};
GN Name=trkA {ECO:0000313|EMBL:ELZ92082.1};
GN ORFNames=C452_05658 {ECO:0000313|EMBL:ELZ92082.1};
OS Haloferax alexandrinus JCM 10717.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=1227458 {ECO:0000313|EMBL:ELZ92082.1, ECO:0000313|Proteomes:UP000011577};
RN [1] {ECO:0000313|EMBL:ELZ92082.1, ECO:0000313|Proteomes:UP000011577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10717 {ECO:0000313|EMBL:ELZ92082.1,
RC ECO:0000313|Proteomes:UP000011577};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ92082.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOLL01000011; ELZ92082.1; -; Genomic_DNA.
DR RefSeq; WP_006600484.1; NZ_AOLL01000011.1.
DR AlphaFoldDB; M0I7W2; -.
DR PATRIC; fig|1227458.3.peg.1094; -.
DR Proteomes; UP000011577; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 2..127
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 139..220
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 229..352
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 364..445
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 445 AA; 47760 MW; 524868D9CA8A6FFA CRC64;
MRVIIIGAGQ VGSSIAADLD ETHEVVVIDC DPERVDELNY SLDVLALHGD GTSVDTLEEA
DVERADMVIA STDDDETNIV ACATAKAISN AFTIARVKNT EYLRTWQRSE KAFGIDFMVC
TNLLAAESIV RVVGLPAARD VDPFAGGQVQ MAEFEVNEES PVANQTVSEA DRFDSLTFAA
ILRDGEVTIP RGDSVIGPGD RVVVIGSPKS VQGFASSVSP DEPPGTAEEV VIVGGSEIGY
HVARLLEERG FKPRLIEHDA ERARELAEML PGTIVMESDA TDVDFLEREY IGDADLLVSA
LDSDEKNLLV SLLAARLGVE RTVAVIDTTP YVDLFEAVGV DVGVSPREVV AEEITRFTRE
GGAENVALIE SDKAEVLEIE VDAESVLAGK PIRESVATLP EGVVIGAITR RREFITPRGD
TVIEPGDHVV VFVDSCVIDD VTPNL
//
