ID   M0IZT5_9EURY            Unreviewed;       484 AA.
AC   M0IZT5;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   ORFNames=C438_14591 {ECO:0000313|EMBL:EMA01593.1};
OS   Haloferax denitrificans ATCC 35960.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=662478 {ECO:0000313|EMBL:EMA01593.1, ECO:0000313|Proteomes:UP000011553};
RN   [1] {ECO:0000313|EMBL:EMA01593.1, ECO:0000313|Proteomes:UP000011553}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35960 {ECO:0000313|EMBL:EMA01593.1,
RC   ECO:0000313|Proteomes:UP000011553};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA01593.1}.
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DR   EMBL; AOLP01000017; EMA01593.1; -; Genomic_DNA.
DR   AlphaFoldDB; M0IZT5; -.
DR   PATRIC; fig|662478.6.peg.2867; -.
DR   Proteomes; UP000011553; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR030665; KaiC.
DR   InterPro; IPR014774; KaiC-like_dom.
DR   InterPro; IPR010624; KaiC_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42926; -; 1.
DR   PANTHER; PTHR42926:SF1; KAIC-LIKE PROTEIN 2; 1.
DR   Pfam; PF06745; ATPase; 2.
DR   PIRSF; PIRSF039117; KaiC; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51146; KAIC; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          6..241
FT                   /note="KaiC"
FT                   /evidence="ECO:0000259|PROSITE:PS51146"
FT   DOMAIN          243..477
FT                   /note="KaiC"
FT                   /evidence="ECO:0000259|PROSITE:PS51146"
SQ   SEQUENCE   484 AA;  52688 MW;  48C5A64022B7588F CRC64;
     MTNLPPRLST GISGLDAVLD GGLVPNRTYM VRGESGAGKT IVGYHFLTAG RENDEDVLFI
     SFEESDADLR ANAETLGFDL SEVPILDLGP SPEAFLDDEA YTMLSPGEVE GKSTANELRE
     AIEEHDPDRV VIDPLSQLGR LSSDRYQFRR LVSSLLSYLK QSGATTLFTS QPSSGGTDET
     LAYLCDGSIS LSRSDWGRSV RIEKFRGSDS QTGPHGMRID GGHGMRVFPR LVPDSHHREF
     TIEPLSSGID DLDALLGGGI ERGSITLVSG PSGVGKSTTG AAFARATAER GERAAVYLFE
     ESKRSFRHRS ESIGIPIDDL IEAGGLRVDA VEPLSLSTDE FAQRVRAEVE ANDTKFVLID
     GTAGYQLSLT DERSDIRREL HALARYLKNM GVTVVLTEEV QQVTGAFHAS DNHVSYLADN
     ILFIRYIEVR GEIRKAVGVL KKRFGGFEPT LRSFEIGTDG ITVGEPLDEL RGILTGTPTW
     NEAE
//