ID   M0PI51_9EURY            Unreviewed;       409 AA.
AC   M0PI51;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Putative perforin {ECO:0000313|EMBL:EMA69578.1};
GN   ORFNames=C468_01225 {ECO:0000313|EMBL:EMA69578.1};
OS   Halorubrum kocurii JCM 14978.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1230456 {ECO:0000313|EMBL:EMA69578.1, ECO:0000313|Proteomes:UP000011546};
RN   [1] {ECO:0000313|EMBL:EMA69578.1, ECO:0000313|Proteomes:UP000011546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 14978 {ECO:0000313|EMBL:EMA69578.1,
RC   ECO:0000313|Proteomes:UP000011546};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA69578.1}.
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DR   EMBL; AOJH01000009; EMA69578.1; -; Genomic_DNA.
DR   AlphaFoldDB; M0PI51; -.
DR   TCDB; 1.C.39.4.4; the membrane attack complex/perforin (macpf) family.
DR   PATRIC; fig|1230456.3.peg.226; -.
DR   Proteomes; UP000011546; Unassembled WGS sequence.
DR   InterPro; IPR020864; MACPF.
DR   Pfam; PF01823; MACPF; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   4: Predicted;
FT   DOMAIN          1..273
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
SQ   SEQUENCE   409 AA;  46020 MW;  D2FDD899AFF725F3 CRC64;
     MSLFDLGESA EFDTAGGLFY KPETVRVQWL EDANITATSG TRASDYQSNL AAQVGLDGGY
     GFFKGSLEFQ FNERQRRSTV FNFVTQTDQY DIALLTLDPS VPVRNLLRER AADDLETLEP
     AVLFDRYGTH YLHSLIVGAA ATYSAATNTT RYSSDVDFTV AAEMSYRGAT GQLSAEQRTQ
     YSEAIEEFRK ASTIEVHARG GQAEFAGKIV DGLYDDWRES IRQNLVFVSL NPDSLRPLWE
     LCETPARRAQ LEAAYEGYAS GFAPEPEPTI APVYGYLVDN PRRWYFSLST SDMPNHGWIL
     EKNPFFYVST VPEEGRVPVY RQSAPNPIRY KLSVDPTGRN GWSDESDSEP VWYAYPPDDG
     DKPGREAIYG YVSPFRPGEA GWFYNVRDGD RGWNRRELAF FADDVDGES
//