ID M0PK33_9EURY Unreviewed; 869 AA.
AC M0PK33;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=C462_10667 {ECO:0000313|EMBL:EMA70303.1};
OS Halorubrum arcis JCM 13916.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum; Halorubrum distributum group.
OX NCBI_TaxID=1230455 {ECO:0000313|EMBL:EMA70303.1, ECO:0000313|Proteomes:UP000011528};
RN [1] {ECO:0000313|EMBL:EMA70303.1, ECO:0000313|Proteomes:UP000011528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13916 {ECO:0000313|EMBL:EMA70303.1,
RC ECO:0000313|Proteomes:UP000011528};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA70303.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOJJ01000071; EMA70303.1; -; Genomic_DNA.
DR RefSeq; WP_007995782.1; NZ_AOJJ01000071.1.
DR AlphaFoldDB; M0PK33; -.
DR STRING; 1230455.C462_10667; -.
DR PATRIC; fig|1230455.3.peg.2056; -.
DR Proteomes; UP000011528; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..692
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 698..716
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..801
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..380
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 670..797
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 823..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 869 AA; 91948 MW; 6BF2D120F5F8192E CRC64;
MDPITRLFGA ITDRVIEQPR RVVIACLVVT ALFAPGMALL EASAGSDQFT DGIEEADALD
RVNERFEPAF GGDDPTTQLI QRDANVLDRR GLLDMLATAE RLDERDGLRV TDFSAPAMDV
AAELDEDADT PAAARDAIER ASDGEIDDAV DAAAEDPGFA TLLSDDFNEE SGTASASLGV
VSHSFPASAD TQAIQSEART VAEEAPGDIT AFGGGIVDDE FERVIFDSLS IVVPAALAVI
LGLLAYAYRD PFDFVLGGIA LLMTVVWTFG FTGYAGIAFS EVLIAVPVLL LAIGIDFGIH
TVNRYREDRA AGAPPETAMR GALGQLVVAY SIIAGTTIIG FLANLTSSLP PLREFGLVAG
LGICFTLVIF VGFLPAAKLL LDRWRAKRSL PEFGSRPLGA EDSALGRFLP KLSAISRPAP
AVFLVVVLLI TAGAAGYGAG VDTTFEDDDF LPPSEEPAYI DYFPGPLQPG EYTATETINF
LSDNFATSED DTVTIYVERR MTSDSALRSL ARAERDPPDS FVTVDGRASA ESVQTAIDAY
ADENPEFEQL VEESSLDDGR PNRNLDRIYA ELRDSGYDDF TGEYLADDSR STRIVYAVES
DASDAEITAD ARRVADRYRG DATATGQIVV FQAVADTIFD SAIVSLAAAL GLSAVFLVIL
FWLLLGSPTL GLVTLVPVTV AVATLTATMR LAGIPFNAIT ATILAITIGL GVDYTVHVAH
RFHDEYPRGG DVDAAVVTTL RGTGGALTGT WATTALGTGV LVLAITPILG QFGLLTAASI
TLAYLASLIV LPPALVVWVA VVERRPGLLF VGRFLDAADV ISTDESDAPD PARTDGGTDA
SAGDADSGGD AFEWQTDPRP PAEDPSQKR
//
