ID   M0ZHB0_SOLTU            Unreviewed;       504 AA.
AC   M0ZHB0;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   SubName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000313|EnsemblPlants:PGSC0003DMT400000784};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400000784, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400000784}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400000784};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|RuleBase:RU004447}.
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DR   AlphaFoldDB; M0ZHB0; -.
DR   STRING; 4113.M0ZHB0; -.
DR   EnsemblPlants; PGSC0003DMT400000784; PGSC0003DMT400000784; PGSC0003DMG400000289.
DR   Gramene; PGSC0003DMT400000784; PGSC0003DMT400000784; PGSC0003DMG400000289.
DR   HOGENOM; CLU_009902_5_1_1; -.
DR   InParanoid; M0ZHB0; -.
DR   OMA; ETGRTHF; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M0ZHB0; baseline.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   PANTHER; PTHR11851:SF190; MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   DOMAIN          85..230
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          237..421
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   504 AA;  54686 MW;  F6AF3A8567319A32 CRC64;
     MYRCASSRLS SLKARQGNRV LTRFSSSAAV ATKPSGGLFS WITGDTSSSV TPLDFPLNDV
     KLSPPLPDYV EPAKTQITTL ANGLKVASEA SVNPAASIGL YVDCGSIYET PASYGATHLL
     ERMAFKSTLN RSHLRIVREI EAIGGNVTAS ASREHMIYTY DALKTYVPQM VEMLADCVRN
     PAFLDWEVKE QLEKVKAEIS EYSKNPQHLL LEAVHSAGYA GPYGNSLMAT EATINRLNST
     VLEDFVAENY TAPRMVLAAS GVEHEEFLKV AEPLLSDLPK VATTEEPKPV YVGGDYRCQA
     DAEMTHFALA FEVPGGWMSE KESMTLTVLQ MLMGGGGSFS AGGPGKGMYS RLYLRVLNQY
     PQIHAFSAFS SIYNSTGLFG IQGTTSSDFG PQAVDVAVKE LIAVANPSEV DQVQLNRAKQ
     ATKSAILMNL ESRMVASEDI GRQLLTYGER KPVEHFLKAI DAVSAKDIAS FVQKLISSPL
     TMASYGDVLS LPSYDAVSSR FRSK
//