ID   M1AF33_SOLTU            Unreviewed;       292 AA.
AC   M1AF33;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=3-beta hydroxysteroid dehydrogenase/isomerase {ECO:0000313|EnsemblPlants:PGSC0003DMT400021417};
GN   Name=102587902 {ECO:0000313|EnsemblPlants:PGSC0003DMT400021417};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400021417, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400021417}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400021417};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; M1AF33; -.
DR   EnsemblPlants; PGSC0003DMT400021417; PGSC0003DMT400021417; PGSC0003DMG400008307.
DR   Gramene; PGSC0003DMT400021417; PGSC0003DMT400021417; PGSC0003DMG400008307.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1AF33; baseline.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05243; SDR_a5; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR15020; FLAVIN REDUCTASE-RELATED; 1.
DR   PANTHER; PTHR15020:SF50; NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13460; NAD_binding_10; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        184..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          64..262
FT                   /note="NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF13460"
SQ   SEQUENCE   292 AA;  31441 MW;  6AAA7C35DFB7F506 CRC64;
     MATATGLFFL TTSAFSVTSK RPSVSLLVNK VHSFRLRAAN IEGSEIEGKE EVGISEKKKI
     FVAGATGNTG KRIVEQLLAK GFAVKAGVLD VDKAKSTLPG QNPDLQIVKA DVTEGSAKLA
     DAIGDDSDAV ICATGFQPSW NLLTPWKVDN FGTVNLVDAC QKLGINRFIL ISSILVNGAA
     MGQLFNPVYI ILNVMGLVLV AKLQAERYIR KSGINYTIIR PGGLKNDPPQ GNIVMQPEDT
     LFRGSISRDQ VAEVAVEALL HPESHYKVVE IVASTDAPKR SFEELFGSIE QQ
//