ID M1BEG6_SOLTU Unreviewed; 373 AA.
AC M1BEG6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=NAD-dependent isocitrate dehydrogenase {ECO:0000313|EnsemblPlants:PGSC0003DMT400043338};
GN Name=102603033 {ECO:0000313|EnsemblPlants:PGSC0003DMT400043338};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400043338, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400043338}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400043338};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR RefSeq; XP_006365305.1; XM_006365243.2.
DR AlphaFoldDB; M1BEG6; -.
DR STRING; 4113.M1BEG6; -.
DR PaxDb; 4113-PGSC0003DMT400043338; -.
DR EnsemblPlants; PGSC0003DMT400043338; PGSC0003DMT400043338; PGSC0003DMG400016826.
DR GeneID; 102603033; -.
DR Gramene; PGSC0003DMT400043338; PGSC0003DMT400043338; PGSC0003DMG400016826.
DR KEGG; sot:102603033; -.
DR eggNOG; KOG0784; Eukaryota.
DR HOGENOM; CLU_031953_0_1_1; -.
DR InParanoid; M1BEG6; -.
DR OMA; GIWPELM; -.
DR OrthoDB; 143577at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0006102; P:isocitrate metabolic process; IBA:GO_Central.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IBA:GO_Central.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR004434; Isocitrate_DH_NAD.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR NCBIfam; TIGR00175; mito_nad_idh; 1.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF42; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 45..368
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 373 AA; 40415 MW; EA7B04DA23D64C80 CRC64;
MAKRTLPILK HFLTSLSPSP SPSHALTSVR SVTYMPRPGD GTPRAVTLIP GDGIGPLVTG
AVEQVMEAMH APVYFERYDV HGDMKSMPPD VMDSIRKNKV CLKGGLKTPV GGGVSSLNVQ
LRKELDLYAS LVHCFNLKGL PTRHENVDIV VIRENTEGEY SGLEHEVVPG VVESLKVMTK
FCSERIAKYA FEYAYLNNRK VVTAVHKANI MKLADGLFLE SCREIASKYP GIKYSEIIVD
NCCMQLVSKP EQFDVMVTPN LYGNLVANTA AGIAGGTGVM PGGNVGADHA VFEQGASAGN
VGNDKILELK KANPIALFLS SAMMLRHLQF PSFADRLETS VKRVIAEGKY MTKDLGGDCT
TQEITDAVIA NLD
//
