ID   M1BR59_SOLTU            Unreviewed;       546 AA.
AC   M1BR59;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=sphinganine-1-phosphate aldolase {ECO:0000256|ARBA:ARBA00038965};
DE            EC=4.1.2.27 {ECO:0000256|ARBA:ARBA00038965};
DE   AltName: Full=Sphingosine-1-phosphate aldolase {ECO:0000256|ARBA:ARBA00042568};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400051021, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400051021}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400051021};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family. Sphingosine-
CC       1-phosphate lyase subfamily. {ECO:0000256|ARBA:ARBA00038302}.
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DR   AlphaFoldDB; M1BR59; -.
DR   STRING; 4113.M1BR59; -.
DR   PaxDb; 4113-PGSC0003DMT400051021; -.
DR   EnsemblPlants; PGSC0003DMT400051021; PGSC0003DMT400051021; PGSC0003DMG400019810.
DR   Gramene; PGSC0003DMT400051021; PGSC0003DMT400051021; PGSC0003DMG400019810.
DR   eggNOG; KOG1383; Eukaryota.
DR   InParanoid; M1BR59; -.
DR   OMA; DPHKMGL; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1BR59; baseline.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008117; F:sphinganine-1-phosphate aldolase activity; IBA:GO_Central.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0030149; P:sphingolipid catabolic process; IBA:GO_Central.
DR   Gene3D; 6.10.140.2150; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR42735; -; 1.
DR   PANTHER; PTHR42735:SF6; SPHINGOSINE-1-PHOSPHATE LYASE 1; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   MOD_RES         326
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   546 AA;  60510 MW;  D14B438C35C96AB4 CRC64;
     MAFPIPPWLN QYRASANSFL SQYEPLILLI TPLFSLLIAR ILQSIFLVIH ERGLKATIIS
     FVMSAIKLVP GVKKYIDSEK QKIVDKLQGS SNRDGWRTEL PKTGLGDNVL VQMRDEKQKD
     VTWQGKCSGT VYIGGNENEG HFSLINEACS MFAHTNPLHL SVFPSVVRFE AEVVAMTAAI
     LGSKEKASGG QICGNMTSGG TESILLAVKS SRDYMKAKKG ITKPEMIIPV SAHSAYDKAA
     QYFKIKLWRV PVDKEFRADV KAIKRYINKN TIMELGDLAS SYQICFHVDL CLGGFVLPFA
     RKLGYPVPPF DFTVQGVTSI SVDVHKYGLA PKGTSVVLYR NREIRKKKKL YSLYLQKRGN
     HSYEVLMTYI PCIHMIVTEW TGGLYVSPTI AGSRAGGLIA GAWAAMISLG SEGYLENTKE
     IMEASKRIQK GIQDIPELFV IGRPDMSIIA FGSDVVDIFE VNDILSSKGW HLNALQRPNS
     VHICVTLQHV SVVQIFLKDL RDSVQTVKEN PGPVNGGFAP IYGAAGKMPD RVMVQDLLVE
     FMDSSY
//