ID M1CXE9_SOLTU Unreviewed; 249 AA.
AC M1CXE9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Ornithine aminotransferase {ECO:0000256|RuleBase:RU365036};
DE EC=2.6.1.13 {ECO:0000256|RuleBase:RU365036};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400076803, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400076803}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400076803};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-
CC glutamate 5-semialdehyde; Xref=Rhea:RHEA:13877, ChEBI:CHEBI:35179,
CC ChEBI:CHEBI:46911, ChEBI:CHEBI:58066, ChEBI:CHEBI:59869; EC=2.6.1.13;
CC Evidence={ECO:0000256|RuleBase:RU365036};
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU365036};
CC -!- PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate
CC 5-semialdehyde from L-ornithine: step 1/1.
CC {ECO:0000256|RuleBase:RU365036}.
CC -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC ECO:0000256|RuleBase:RU365036}.
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DR AlphaFoldDB; M1CXE9; -.
DR STRING; 4113.M1CXE9; -.
DR PaxDb; 4113-PGSC0003DMT400076803; -.
DR EnsemblPlants; PGSC0003DMT400076803; PGSC0003DMT400076803; PGSC0003DMG400029872.
DR Gramene; PGSC0003DMT400076803; PGSC0003DMT400076803; PGSC0003DMG400029872.
DR Gramene; RHC08H1G0798.2.1; RHC08H1G0798.2.1; RHC08H1G0798.2.
DR eggNOG; KOG1402; Eukaryota.
DR HOGENOM; CLU_016922_10_2_1; -.
DR InParanoid; M1CXE9; -.
DR OMA; HDECEAT; -.
DR UniPathway; UPA00098; UER00358.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR GO; GO:0004587; F:ornithine aminotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019544; P:arginine catabolic process to glutamate; IEA:EnsemblPlants.
DR GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblPlants.
DR GO; GO:0042538; P:hyperosmotic salinity response; IEA:EnsemblPlants.
DR GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0051646; P:mitochondrion localization; IEA:EnsemblPlants.
DR GO; GO:0006593; P:ornithine catabolic process; IEA:EnsemblPlants.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR PANTHER; PTHR11986:SF18; ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000256|RuleBase:RU365036};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU365036};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transferase {ECO:0000256|RuleBase:RU365036}.
SQ SEQUENCE 249 AA; 27177 MW; 9617EC3500A97410 CRC64;
MLPHNICLTL QVIIPPEGYL KAVRDLCSKY NILMIADEIQ SGLARSGRLL ACDWEEVRPD
VVILGKALGG GVLPVSAVLA DKDVMLCIQA GEHGSTFGGN PLASAVAIAS LDVIRDEGLA
ERSAQMGEQL RHQLIKIQRQ FPHFIKEVRG KGLFNAVELN SKSLLPVTAY DICMKLKERG
ILAKPTHDSI IRLTPPLSMS LEELQEGSNA LHDVLVHDLP KMQKEKPARV SHATSNVCDR
CGRDLYGSS
//
