ID   M1D6X6_SOLTU            Unreviewed;       539 AA.
AC   M1D6X6;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Bacterial spot disease resistance protein 4 {ECO:0000313|EnsemblPlants:PGSC0003DMT400083473};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400083473, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400083473}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400083473};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; M1D6X6; -.
DR   EnsemblPlants; PGSC0003DMT400083473; PGSC0003DMT400083473; PGSC0003DMG400033334.
DR   Gramene; PGSC0003DMT400083473; PGSC0003DMT400083473; PGSC0003DMG400033334.
DR   HOGENOM; CLU_001561_2_2_1; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1D6X6; baseline.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11017:SF433; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   DOMAIN          91..313
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   539 AA;  63414 MW;  ACB476D496A6EE50 CRC64;
     MWMHHMFDTK SESFAEAFAK HESRYKDDVE GMQKVQRWRT ALTAAANLKG HEFPNSGESD
     ADCIKRIVDQ ISSKCNTSVS YLQEVVGIDT QLKKVESLLK MEINDVRIVW IWGMGGIGKT
     TLAKTIFYKL SSQFEINDVC FLENIKEKKH KMHSLQNILL SKLLREKDNC VKDKEEGRNL
     LATRLKCKKV LIVLDDIDHG DQMEYLANDL GWFDKGSRII ATTRDQRLIG ENHVVYEMET
     LLDRDAIKLF ELYAFKKKVP NECFKDLTLE IVSLAKGHPL ALKVWGSSLH RMDITEWKSA
     MVRIKKNSNV EITKNLKISY DGLEREEQQI FLDIACFFRG IEKEEVMQVL ESCYFGPKFG
     LRVLVNKSLV SISEYDTIEM HDLIQDMGKY IVQRRKHPEK HSRLWNVEHF NEVVDNNMGT
     MPVKAIWFTY CQQQSFNKEA MKNMTRLRIL CIRGDKYDLF FSSDSNSHDG STDGSIEYLS
     NNLRWFVWHE YPWKLLPRNF EPKKLVHLEL RWSSLHYLWN ETKVPFYLRY FLFYLVLEL
//