ID M1IPM9_9CREN Unreviewed; 156 AA.
AC M1IPM9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Riboflavin synthase {ECO:0000256|ARBA:ARBA00013950, ECO:0000256|PIRNR:PIRNR015750};
DE EC=2.5.1.9 {ECO:0000256|ARBA:ARBA00012827, ECO:0000256|PIRNR:PIRNR015750};
GN ORFNames=SacN8_03980 {ECO:0000313|EMBL:AGE70767.1};
OS Sulfolobus acidocaldarius N8.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=1028566 {ECO:0000313|Proteomes:UP000011281};
RN [1] {ECO:0000313|EMBL:AGE70767.1, ECO:0000313|Proteomes:UP000011281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N8 {ECO:0000313|EMBL:AGE70767.1,
RC ECO:0000313|Proteomes:UP000011281};
RX PubMed=22418622; DOI=10.1038/ismej.2012.20;
RA Mao D., Grogan D.;
RT "Genomic evidence of rapid, global-scale gene flow in a Sulfolobus
RT species.";
RL ISME J. 6:1613-1616(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-
CC ribitylamino)uracil + riboflavin; Xref=Rhea:RHEA:20772,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15934, ChEBI:CHEBI:57986,
CC ChEBI:CHEBI:58201; EC=2.5.1.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000968,
CC ECO:0000256|PIRNR:PIRNR015750};
CC -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis; riboflavin
CC from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-
CC ribitylamino)uracil: step 2/2. {ECO:0000256|ARBA:ARBA00004887}.
CC -!- SIMILARITY: Belongs to the DMRL synthase family.
CC {ECO:0000256|ARBA:ARBA00007424, ECO:0000256|PIRNR:PIRNR015750}.
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DR EMBL; CP002817; AGE70767.1; -; Genomic_DNA.
DR RefSeq; WP_011277690.1; NC_020246.1.
DR AlphaFoldDB; M1IPM9; -.
DR GeneID; 78441168; -.
DR KEGG; sacn:SacN8_03980; -.
DR PATRIC; fig|1028566.6.peg.778; -.
DR HOGENOM; CLU_1682776_0_0_2; -.
DR UniPathway; UPA00275; UER00405.
DR Proteomes; UP000011281; Chromosome.
DR GO; GO:0009349; C:riboflavin synthase complex; IEA:InterPro.
DR GO; GO:0004746; F:riboflavin synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd09210; Riboflavin_synthase_archaeal; 1.
DR Gene3D; 3.40.50.960; Lumazine/riboflavin synthase; 1.
DR InterPro; IPR002180; LS/RS.
DR InterPro; IPR036467; LS/RS_sf.
DR InterPro; IPR006399; Ribfl_synth_arc.
DR NCBIfam; TIGR01506; ribC_arch; 1.
DR Pfam; PF00885; DMRL_synthase; 1.
DR PIRSF; PIRSF015750; Ribfl_synth_arc; 1.
DR SUPFAM; SSF52121; Lumazine synthase; 1.
PE 3: Inferred from homology;
KW Riboflavin biosynthesis {ECO:0000256|ARBA:ARBA00022619,
KW ECO:0000256|PIRNR:PIRNR015750};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR015750}.
SQ SEQUENCE 156 AA; 17057 MW; 00FEDC9FCB05DE46 CRC64;
MRRKYGVADT TFSRIDMGAI AIKTITKEDP DAEIVRYTVP GIKDLPVAAK RLLDSGCDGV
ITLGWVGKSM LDKYSYLAAS IGLITTQIIT SKHVIDVTIH EDEAEDEEQL KNIAIDRVTK
HSINLVKLIR DGKNSLTPFA GKGLRQGYGN AGPIED
//
