ID   M1JLA2_ENCCN            Unreviewed;       537 AA.
AC   M1JLA2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Enhancer of zeste protein {ECO:0000313|EMBL:AGE96309.1};
GN   ORFNames=ECU09_1750 {ECO:0000313|EMBL:AGE96309.1};
OS   Encephalitozoon cuniculi (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=6035 {ECO:0000313|EMBL:AGE96309.1};
RN   [1] {ECO:0000313|EMBL:AGE96309.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23376943; DOI=10.1128/EC.00307-12;
RA   Selman M., Sak B., Kvac M., Farinelli L., Weiss L.M., Corradi N.;
RT   "Extremely Reduced Levels of Heterozygosity in the Vertebrate Pathogen
RT   Encephalitozoon cuniculi.";
RL   Eukaryot. Cell 12:496-502(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KC513616; AGE96309.1; -; Genomic_DNA.
DR   AlphaFoldDB; M1JLA2; -.
DR   VEuPathDB; MicrosporidiaDB:AEWD_091800; -.
DR   VEuPathDB; MicrosporidiaDB:AEWQ_091780; -.
DR   VEuPathDB; MicrosporidiaDB:AEWR_091760; -.
DR   VEuPathDB; MicrosporidiaDB:ECU09_1750; -.
DR   VEuPathDB; MicrosporidiaDB:M970_091760; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR006560; AWS_dom.
DR   InterPro; IPR026489; CXC_dom.
DR   InterPro; IPR045318; EZH1/2-like.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR45747; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR   PANTHER; PTHR45747:SF4; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS51215; AWS; 1.
DR   PROSITE; PS51633; CXC; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
FT   DOMAIN          306..409
FT                   /note="CXC"
FT                   /evidence="ECO:0000259|PROSITE:PS51633"
FT   DOMAIN          359..401
FT                   /note="AWS"
FT                   /evidence="ECO:0000259|PROSITE:PS51215"
FT   DOMAIN          395..524
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
SQ   SEQUENCE   537 AA;  60741 MW;  FC534EB1A15553FE CRC64;
     MSSRRIGSNL QLMTSSLTNE SINSCSKLWR LLFPMGENDG RNKLGKTLLD PASGMHKSTS
     LELRKEAGQV LMIDDKHPSP SEGRRSKVGG FQTSVVKIVI PRIDPGPRGA FFTFTNTSIR
     TEDDPALRFI PYMPGTSGFI SLSEFKEMEL VKGFCDPGEG DIGQVLRKEH DLGHGKDHRM
     PEKCGWDDEL LMMRKLFCSV CFIFGCKWHS RTEGICIKPV GFEKDMLNAH IEPWGVCGDA
     CKKMKSLCSD TARNGLEQDA YDALCRACEE SQGYECIASL LFYFRFRRYV SCEKIREASM
     VLMGRHRYVV GNKNRSNVDV AAFFTPCDHP GSCTEGNGCT CISNRTNCEM SCLCTECRNF
     FMGCRCPAKC NSKCACRQES RECTQVCLCK QCGNKDLQMG KAAPTFVAPS RVEGYGLFAK
     EKMSKGRFVI EYVGEIISNE EAERRGTFYD LRGCSYLFDL YSREGKALYV IDSRFIGNRS
     RFINHSQRNS NLYAFVLIVN GVRRIGFYAS RDICEGEELL FDYKYSEEHK RKHNIAD
//