ID   M1KB57_ENCCN            Unreviewed;       350 AA.
AC   M1KB57;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=PDEase domain-containing protein {ECO:0000259|Pfam:PF00233};
OS   Encephalitozoon cuniculi (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=6035 {ECO:0000313|EMBL:AGE96440.1};
RN   [1] {ECO:0000313|EMBL:AGE96440.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23376943; DOI=10.1128/EC.00307-12;
RA   Selman M., Sak B., Kvac M., Farinelli L., Weiss L.M., Corradi N.;
RT   "Extremely Reduced Levels of Heterozygosity in the Vertebrate Pathogen
RT   Encephalitozoon cuniculi.";
RL   Eukaryot. Cell 12:496-502(2013).
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DR   EMBL; KC513619; AGE96440.1; -; Genomic_DNA.
DR   AlphaFoldDB; M1KB57; -.
DR   VEuPathDB; MicrosporidiaDB:AEWD_090820; -.
DR   VEuPathDB; MicrosporidiaDB:AEWQ_090810; -.
DR   VEuPathDB; MicrosporidiaDB:AEWR_090800; -.
DR   VEuPathDB; MicrosporidiaDB:ECU09_0790; -.
DR   VEuPathDB; MicrosporidiaDB:M970_090800; -.
DR   OMA; VELAFEC; -.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.1300.10; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 1.
DR   InterPro; IPR002073; PDEase_catalytic_dom.
DR   InterPro; IPR036971; PDEase_catalytic_dom_sf.
DR   Pfam; PF00233; PDEase_I; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   4: Predicted;
FT   DOMAIN          94..288
FT                   /note="PDEase"
FT                   /evidence="ECO:0000259|Pfam:PF00233"
SQ   SEQUENCE   350 AA;  39804 MW;  CE820F52979851B9 CRC64;
     MIDQGKEVSK DIRDAIVKTI QNKKNFCSRP TGDLRLSLSS YRLFHLENIS LADGVATAME
     TLVKDPRFHL LGIRPETLSS FFSFSFFHML PQRYHNLDHL VNTLCFGDFI LQRLGEGGYT
     LPILDKMCLM IALGLHDIGH PGERNRGKIG ALSSSYGGPK AISFELIHAS ICRKMVSAYR
     HTLFAGLDDA ETERRQGFIE KMIFATDLKL NAEIIGAFDA KYFEKETQGS MERRVRNGVG
     GEISEIELMM IMKIADLSSC YKDYRIFNKN SIAFWAEVYD DDDYNRTLEN ISEDIDLLEG
     ISIPLADSFS LVFGDLRFLY DQALANLREH RKYYRRLKAQ GSPKHPLAGE
//