ID M1MK42_9CLOT Unreviewed; 441 AA.
AC M1MK42;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Flagellar biosynthesis protein FlhF {ECO:0000256|ARBA:ARBA00014919};
DE AltName: Full=Flagella-associated GTP-binding protein {ECO:0000256|ARBA:ARBA00030866};
GN Name=flhF {ECO:0000313|EMBL:AGF58259.1};
GN ORFNames=Cspa_c45060 {ECO:0000313|EMBL:AGF58259.1};
OS Clostridium saccharoperbutylacetonicum N1-4(HMT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=931276 {ECO:0000313|EMBL:AGF58259.1, ECO:0000313|Proteomes:UP000011728};
RN [1] {ECO:0000313|EMBL:AGF58259.1, ECO:0000313|Proteomes:UP000011728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N1-4(HMT) {ECO:0000313|Proteomes:UP000011728};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium saccharoperbutylacetonicum N1-4(HMT).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for flagellar biosynthesis. May be involved in
CC translocation of the flagellum. {ECO:0000256|ARBA:ARBA00025337}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC {ECO:0000256|ARBA:ARBA00008531}.
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DR EMBL; CP004121; AGF58259.1; -; Genomic_DNA.
DR RefSeq; WP_015394570.1; NZ_AOIF01000032.1.
DR AlphaFoldDB; M1MK42; -.
DR STRING; 36745.CLSAP_42680; -.
DR KEGG; csr:Cspa_c45060; -.
DR PATRIC; fig|931276.5.peg.4542; -.
DR eggNOG; COG1419; Bacteria.
DR HOGENOM; CLU_009301_11_4_9; -.
DR OrthoDB; 9778554at2; -.
DR Proteomes; UP000011728; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR CDD; cd17873; FlhF; 1.
DR Gene3D; 1.20.120.1380; Flagellar FlhF biosynthesis protein, N domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020006; FlhF.
DR InterPro; IPR047040; FlhF__GTPase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000897; SRP54_GTPase_dom.
DR NCBIfam; TIGR03499; FlhF; 1.
DR PANTHER; PTHR43134:SF3; FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; 1.
DR PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00448; SRP54; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00962; SRP54; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Bacterial flagellum protein export {ECO:0000256|ARBA:ARBA00023225};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:AGF58259.1};
KW Cilium {ECO:0000313|EMBL:AGF58259.1};
KW Flagellum {ECO:0000313|EMBL:AGF58259.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000011728};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 244..391
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 245..436
FT /note="SRP54-type proteins GTP-binding"
FT /evidence="ECO:0000259|SMART:SM00962"
SQ SEQUENCE 441 AA; 49899 MW; C5207FE18B6C9CD4 CRC64;
MIIKKYLVKD MNEGLTRIRY ELGKDAIIIS QRKVRRPGII GLLSKKLIEV TAAVENSTDQ
EKDNRSFKQD KNYYKQKDEE EEFRNSLESI KKLMQNEMLS SNSNNIIKEE VKAETLFDKI
LEHNTNVEKE TAKSKEENIP QINKADKTKI KAVKSNDEEN SSMESIHKEV TELKDLLNKV
IKTGTYGEIS ENLLQERLKD LDIDEALQED ILSVAETMKT EDIDEIEILR DVFERDILVA
RQNLTGRVVL VGPTGVGKTT TIAKLAGRLA LVEKKKVGLI TVDTYRIGAI EQLKTYAEIM
NIPFKVVITM KEMEEAIEAM KECDVILIDT TGRSSKNAMQ ISELRAFVQK ANPDHVDMVI
SATTKNSDIK SILKGYAELD FDNIIITKLD ETTVYGSLYN IAKLSNKPVS FITIGQNVPD
DIMVPTKEKI ASFILGEEII C
//
