ID   M1RGZ2_FELCA            Unreviewed;       540 AA.
AC   M1RGZ2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Keratin 73 {ECO:0000313|EMBL:AGG09186.1};
GN   Name=KRT73 {ECO:0000313|EMBL:AGG09186.1};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|EMBL:AGG09186.1};
RN   [1] {ECO:0000313|EMBL:AGG09186.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23770706;
RA   Gandolfi B., Alhaddad H., Joslin S.E., Khan R., Filler S., Brem G.,
RA   Lyons L.A.;
RT   "A splice variant in KRT71 is associated with curly coat phenotype of
RT   Selkirk Rex cats.";
RL   Sci. Rep. 3:2000-2000(2013).
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   EMBL; KC189046; AGG09186.1; -; mRNA.
DR   RefSeq; NP_001277164.1; NM_001290235.1.
DR   AlphaFoldDB; M1RGZ2; -.
DR   GeneID; 101097992; -.
DR   KEGG; fca:101097992; -.
DR   OrthoDB; 4640531at2759; -.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR032444; Keratin_2_head.
DR   InterPro; IPR003054; Keratin_II.
DR   PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45616:SF31; KERATIN, TYPE II CYTOSKELETAL 73; 1.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF16208; Keratin_2_head; 2.
DR   PRINTS; PR01276; TYPE2KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Keratin {ECO:0000256|ARBA:ARBA00022744, ECO:0000313|EMBL:AGG09186.1}.
FT   DOMAIN          132..445
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          507..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          187..235
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          343..423
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        522..540
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  58704 MW;  BACB4B3572F5D9DF CRC64;
     MNRQFTYKSG AAAKGGFSGC SAVLSGGSSS SYRAGGKGLS GGFGSRSLYS LGGARSISLN
     MASGSGRAGG YGFGRNRASG FAGSMFGSVA LGPVCPTVCP PGGIHQVTVN KNLLAPLNVE
     LDPEIQKVRS QEREQIKALN NKFASFIDKV RFLEQQNQVL ETKWELLQQL DLNNCKNNLE
     PILEGYISNL RKQLETLSGD RVRLDSELRS MRDVVEDYKK RYEEEINKRT TAENEFVVLK
     KDVDAAYMSK VELQAKVDAL DGEIKFFKCL YEGEIAQIQS HISDTSVILS MDNNRNLDLD
     SIITEVRAQY EEIALKSKAE AEALYQTKFQ ELQLVAGRHG DDLKHTKNEI SELTRLIQRL
     RSEIESVKKQ CSNLEMAIAD AEQRGDSALK DARAKLDELE AALHQAKEEL ARMLREYQEL
     MSTKLALDVE IATYRKLLEG EECRMSGEHT NSVSISVISS TVAGTTGTGA GFGFSGSGTF
     GYRPSSVSGG YGMLSGGCVT GSGNCGPRGE AKTRLGSASE FKDAQGKTSA LSSPTKKTTR
//