ID M1VFK9_CYAM1 Unreviewed; 980 AA.
AC M1VFK9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=MutS family DNA mismatch repair protein MSH2 {ECO:0000313|EMBL:BAM81757.1};
GN ORFNames=CYME_CMP114C {ECO:0000313|EMBL:BAM81757.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM81757.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM81757.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM81757.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM81757.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM81757.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
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DR EMBL; AP006498; BAM81757.1; -; Genomic_DNA.
DR RefSeq; XP_005537793.1; XM_005537736.1.
DR AlphaFoldDB; M1VFK9; -.
DR STRING; 280699.M1VFK9; -.
DR GeneID; 16996050; -.
DR KEGG; cme:CYME_CMP114C; -.
DR eggNOG; KOG0219; Eukaryota.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000007014; Chromosome 16.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF35; DNA MISMATCH REPAIR PROTEIN MSH2; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007014}.
FT DOMAIN 849..865
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 980 AA; 107363 MW; AAEF1F505941758C CRC64;
MVHVQGAHGS DALVQVFGGV SGVDKFGREW FESQLEADAA VAYDPSTVLL VLQFASTSAG
FWLLSGDAGL LSTQLQTESV RVSVTCQAQQ RVLEWYLARV RASTNATLAT WVLAGLEAGK
AVAVYAAGSR LGSASTSEAR GFGFPLQIAN KWFLAAAGSP ARVGPLTSYL PGNTRAQDSS
GLADGDSVVD AEGIALVGET AGVLAVRTRA TGEQSNTGHR HCRMVAACHC IPHAGLFRVI
ECQEDASGEA FLLTDWIERA LVRSGARELV LQDGDLAEYE LHQLDAALER IGGIARAMLR
PVRRGGLGAE HDLRWLVAES ETPDSCQRDD DAWRPEALTL DEMFSMKLAT DCAHMCVRFL
DLGQRVGERG RYRIEQLAWR QNLQLDAAAL KALHVLWGDE TGPASPSSPP PGSLWCLLDR
CRTPMGSRLL RTALIEPLGN REAIERRLDL VELLVHDVIA RQRLADYHLK GFADLITIAR
RLARDKTSLR QLVRLYQSLV RLPALRSELE DLLLAHTETR PRCCQVLRSD IADRLAAVAP
AAQEFIEDVE RFIDLERITN HEYLLRPSMS TEMTQIRGEM DTCLEEMNRT YQQTIAALQQ
DDGVRGSGGD WLKLERKDGL GFCFRVTRKD EVCIRGKESI TVLETRKDGV RFTTSALRRW
SSAYTAAEQR YVAVQRSTLA QVFGHFAKYA SMLEVLGHVL ALLDMLVAFA MISAERQFCR
PRLVESDEFE AHESSGVILR GLRHPLVELA LQGEHTFVAN DVVLTHPRRL LLITGPNMGG
KSVTLRSVGL AVLMAHCGCF VAADAASLPV VDRILVRVGA GDMQTRGIST FMAEMLDMST
ILRHATSSSL VLVDELGRGT STAEGFGLAA ALCEALASRA SWTLFATHFH ELTKLAQGAW
SHRMLNAHVA VAQVHRDNDD SEINDRGRGT PAASLVFLYE LRPGPSERSF GIHIAEMAGF
PHPVIDMARA KVSALENTDA
//
