ID M1WD21_CLAP2 Unreviewed; 360 AA.
AC M1WD21;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=CPUR_08448 {ECO:0000313|EMBL:CCE34515.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE34515.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE34515.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE34515.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE34515.1}.
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DR EMBL; CAGA01000092; CCE34515.1; -; Genomic_DNA.
DR AlphaFoldDB; M1WD21; -.
DR STRING; 1111077.M1WD21; -.
DR VEuPathDB; FungiDB:CPUR_08448; -.
DR eggNOG; KOG0952; Eukaryota.
DR HOGENOM; CLU_048308_0_0_1; -.
DR OrthoDB; 57056at2759; -.
DR PhylomeDB; M1WD21; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CCE34515.1};
KW Helicase {ECO:0000313|EMBL:CCE34515.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000313|EMBL:CCE34515.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801}.
FT DOMAIN 15..340
FT /note="SEC63"
FT /evidence="ECO:0000259|SMART:SM00973"
SQ SEQUENCE 360 AA; 40835 MW; 470ADDA399218E52 CRC64;
MATSTTPTCG TSISSKDMHE IKIRYRISPA TMKLLSSIPK SPDRQQILHK ACNASELRCF
PLKQTERGFF REINDHTAIP YPIKENISQP WHKVFLLIQV ELLRTGWPNK ISVAARKELY
QELGRMLVLL DRILRCIVDF LGLRRDGRGV NAALDLLRST WSRVWDGDGR ELLSIDGIGA
AKMDKLGRAG VRTIRQIQQL EFCHIERLLS RNPPFGHQLL QKLAGFPRLV CEFESIVQAP
PVPTSQETPP PSGICPWVCR AVMRYENNKP PFWKKDNPWV TLVIEGDDGR LLWFWRGGIQ
KLSESKDLVI CLQTKMGEKI QIRLACEEIV GTMVSMTHQM PEMAKDPGSS ASSCGHVEKL
//
