ID M2QBD3_9PSEU Unreviewed; 426 AA.
AC M2QBD3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:EMD23392.1};
GN ORFNames=C791_7317 {ECO:0000313|EMBL:EMD23392.1};
OS Amycolatopsis azurea DSM 43854.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1238180 {ECO:0000313|EMBL:EMD23392.1, ECO:0000313|Proteomes:UP000014137};
RN [1] {ECO:0000313|EMBL:EMD23392.1, ECO:0000313|Proteomes:UP000014137}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43854 {ECO:0000313|EMBL:EMD23392.1,
RC ECO:0000313|Proteomes:UP000014137};
RA Khatri I., Kaur I., Subramanian S., Mayilraj S.;
RT "Genome assembly of Amycolatopsis azurea DSM 43854.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMD23392.1}.
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DR EMBL; ANMG01000075; EMD23392.1; -; Genomic_DNA.
DR RefSeq; WP_005165539.1; NZ_MUXN01000008.1.
DR AlphaFoldDB; M2QBD3; -.
DR PATRIC; fig|1238180.3.peg.6919; -.
DR OrthoDB; 9763887at2; -.
DR Proteomes; UP000014137; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 336..410
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 426 AA; 43597 MW; 860B2EBA331A92A9 CRC64;
MSAFAAVDVI RAKRDGGRLS DEQIDWTIDA YTRGDLAEEQ MAALAMAIFL RGMDSGEIAR
WTGAMIESGE RLDLKVSRPT IDKHSTGGVG DKITLPLAPL VAACGAAVPQ LSGRGLGHTG
GTLDKLESIP GWRAALSTSE IIRQLDDVGA VVCAATEGLA PADKKLYALR DVTSTVESIP
LIASSIMSKK IAEGSAGLVL DVKTGSGAFM KTLPQARELA RTLVEIGTAH GVATTALITD
MNVPLGNAVG NAIEVAESVE VLRGGGPADV VELTVALARE MLALAGLSDV DPASVLASGK
AYETWCRMIA AQGGDPEAAL PRPKHVHIVS APSSGVLASL DAYSVGVAAW RLGAGRARKE
DPVQAAAGVL CLAKPGDPVS AGQPLLELHT DTPDAVPSAL AALEGAYAVG SSAPDSAPLV
LETVRG
//
