ID M2RKF9_CERS8 Unreviewed; 1092 AA.
AC M2RKF9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Transcription factor BYE1 {ECO:0000256|ARBA:ARBA00021616};
DE Flags: Fragment;
GN ORFNames=CERSUDRAFT_104220 {ECO:0000313|EMBL:EMD38932.1};
OS Ceriporiopsis subvermispora (strain B) (White-rot fungus) (Gelatoporia
OS subvermispora).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Gelatoporiaceae; Gelatoporia.
OX NCBI_TaxID=914234 {ECO:0000313|EMBL:EMD38932.1, ECO:0000313|Proteomes:UP000016930};
RN [1] {ECO:0000313|EMBL:EMD38932.1, ECO:0000313|Proteomes:UP000016930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B {ECO:0000313|EMBL:EMD38932.1,
RC ECO:0000313|Proteomes:UP000016930};
RX PubMed=22434909; DOI=10.1073/pnas.1119912109;
RA Fernandez-Fueyo E., Ruiz-Duenas F.J., Ferreira P., Floudas D.,
RA Hibbett D.S., Canessa P., Larrondo L.F., James T.Y., Seelenfreund D.,
RA Lobos S., Polanco R., Tello M., Honda Y., Watanabe T., Watanabe T.,
RA Ryu J.S., Kubicek C.P., Schmoll M., Gaskell J., Hammel K.E., St John F.J.,
RA Vanden Wymelenberg A., Sabat G., Splinter BonDurant S., Syed K.,
RA Yadav J.S., Doddapaneni H., Subramanian V., Lavin J.L., Oguiza J.A.,
RA Perez G., Pisabarro A.G., Ramirez L., Santoyo F., Master E., Coutinho P.M.,
RA Henrissat B., Lombard V., Magnuson J.K., Kuees U., Hori C., Igarashi K.,
RA Samejima M., Held B.W., Barry K.W., LaButti K.M., Lapidus A.,
RA Lindquist E.A., Lucas S.M., Riley R., Salamov A.A., Hoffmeister D.,
RA Schwenk D., Hadar Y., Yarden O., de Vries R.P., Wiebenga A., Stenlid J.,
RA Eastwood D., Grigoriev I.V., Berka R.M., Blanchette R.A., Kersten P.,
RA Martinez A.T., Vicuna R., Cullen D.;
RT "Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete
RT chrysosporium provide insight into selective ligninolysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:5458-5463(2012).
CC -!- FUNCTION: Negative regulator of transcription elongation.
CC {ECO:0000256|ARBA:ARBA00002311}.
CC -!- SIMILARITY: Belongs to the BYE1 family.
CC {ECO:0000256|ARBA:ARBA00011050}.
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DR EMBL; KB445794; EMD38932.1; -; Genomic_DNA.
DR AlphaFoldDB; M2RKF9; -.
DR STRING; 914234.M2RKF9; -.
DR HOGENOM; CLU_011239_0_0_1; -.
DR OrthoDB; 5491784at2759; -.
DR Proteomes; UP000016930; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd21538; SPOC_TFIIS; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF20; PROTEIN PARTNER OF SNF, ISOFORM B; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016930};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 44..94
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 245..397
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 992..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..487
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 992..1007
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1048..1066
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMD38932.1"
SQ SEQUENCE 1092 AA; 118402 MW; 9440C9DA3A4ED3D8 CRC64;
MTSRPTGRTR QSRASDAASP HNKENATING EKTRGKAKPR VEGKVYCSCR KPDDGTPMIL
CAHCKEWYHF QCLKLSERDA EDIEVYICPP CHEKTGLRSV MEWEGPEAIE EAKQSANRAT
PPNADDIKKE EDANTKMEDA PELPSESEAE SSADDYVAEK SPSHSKRRAR PIPSSDSESE
SIASAKASRT TKRLRRGSAA KKEPARRTVS TSPGPTTQTK RRQSTASQSE TKRMRSGSTS
SDDPARKYCL NKLQEMFCQI FVRYPFFKDD VIAVGDLQPD KKQEELSDEE KEALEHRAKR
FASDLEQCMY EIYSEPDKNG KHGVAGKYKE RFRMLTFNLN QSDRAVLHMR IASGQIPPKE
LSTMSSTDLA SEEAKQSIKQ AEQEALQQTI LKKQALPRAK ITHKGLQDIE DVNGGSPRAA
ERAREDEEEE RIERERLARL RVQTQRSNSG QGSVPPDSPV VPNTPQTPLT PLTPHTPRWG
APPPVPGALH GPQPSELMPP PSVVVPRPPV APLFVPSGSE FVGAPGESEL NLADFINIDD
EPTSDVTLST AEPPLTPTVT AAPVITPIST AQATPTHAAP PTIGISPFAQ RSADERRPSF
DLNALWSPKA ADSNYEHQSG PQEAGHAPMY EEPKEIGESN VISEEAEDQD FDMFLGNDEM
ERATDPSNED AMAQDTPFDV QPTVWNGTLN MPLDSTLAQE VSLVARQGGG RPLGNDSPLW
RALFPSPQLR IDGRVPVDKS AAYLTQTRLN PTKELIAVAF SPAPGTDVSG FQTLIDYLIT
KGRHGLVFPW GNRPKENAPG RELYIVPLLS HEPLPEFMEL LDDLRLPKMR STHYLVGIWV
LTKGKLTAPT TPPPPPAPVQ VPVPAPAPTT APTPTLTIPA FDPSQLQHLI PALTNAHAST
SAAQMPPSAP APVLPAVMTA SNAALAAEVA SLTPEQIQAM LLALQNSGLS PPPPAQPASA
PPPTSTSMTS IPLQPWTAPV AAYPPSYPPA NAYPSQPLPP PAPRQYPDMP YGGYDHGAPY
PPGGGHYDGG GDRGYRGRGG GGAGGGRGRG RGRDRDRPRD TGWPKSRGRG RGGYASAPRG
GGARWGENQQ WS
//
