ID M2RNV1_CERS8 Unreviewed; 763 AA.
AC M2RNV1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=CERSUDRAFT_112346 {ECO:0000313|EMBL:EMD40122.1};
OS Ceriporiopsis subvermispora (strain B) (White-rot fungus) (Gelatoporia
OS subvermispora).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Gelatoporiaceae; Gelatoporia.
OX NCBI_TaxID=914234 {ECO:0000313|EMBL:EMD40122.1, ECO:0000313|Proteomes:UP000016930};
RN [1] {ECO:0000313|EMBL:EMD40122.1, ECO:0000313|Proteomes:UP000016930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B {ECO:0000313|EMBL:EMD40122.1,
RC ECO:0000313|Proteomes:UP000016930};
RX PubMed=22434909; DOI=10.1073/pnas.1119912109;
RA Fernandez-Fueyo E., Ruiz-Duenas F.J., Ferreira P., Floudas D.,
RA Hibbett D.S., Canessa P., Larrondo L.F., James T.Y., Seelenfreund D.,
RA Lobos S., Polanco R., Tello M., Honda Y., Watanabe T., Watanabe T.,
RA Ryu J.S., Kubicek C.P., Schmoll M., Gaskell J., Hammel K.E., St John F.J.,
RA Vanden Wymelenberg A., Sabat G., Splinter BonDurant S., Syed K.,
RA Yadav J.S., Doddapaneni H., Subramanian V., Lavin J.L., Oguiza J.A.,
RA Perez G., Pisabarro A.G., Ramirez L., Santoyo F., Master E., Coutinho P.M.,
RA Henrissat B., Lombard V., Magnuson J.K., Kuees U., Hori C., Igarashi K.,
RA Samejima M., Held B.W., Barry K.W., LaButti K.M., Lapidus A.,
RA Lindquist E.A., Lucas S.M., Riley R., Salamov A.A., Hoffmeister D.,
RA Schwenk D., Hadar Y., Yarden O., de Vries R.P., Wiebenga A., Stenlid J.,
RA Eastwood D., Grigoriev I.V., Berka R.M., Blanchette R.A., Kersten P.,
RA Martinez A.T., Vicuna R., Cullen D.;
RT "Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete
RT chrysosporium provide insight into selective ligninolysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:5458-5463(2012).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; KB445793; EMD40122.1; -; Genomic_DNA.
DR AlphaFoldDB; M2RNV1; -.
DR STRING; 914234.M2RNV1; -.
DR HOGENOM; CLU_004747_6_1_1; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000016930; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016930};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 414..643
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT COILED 248..275
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 763 AA; 88374 MW; 28114CEDCA44B7D6 CRC64;
MANTAGNNMP VAGASLAETW EFLEEGVDHI MTKLQTGMSY SKYMSLYTVA YNYCTSSKMN
NAGDGPGLGH RTGANLMGSD LYNNLIRYFV SHLKDLRTHS DSLQDEALLQ YYAAEWDRYT
TGANYINRLF IYLNRHWVKR ERDEGRKGIY PVYTLALVQW RQNFFMHVQQ KHQKLAGAIL
RLIERQRNGE TIDQGLVKKV VDSFVSLGLD ESDINKVSFE VYREHFEVPF LEATEKYYRQ
ESEAFLAENS VADYLKKAEE RLREEEDRVE RYLNTNTRKP LIGKCEHVLI REHAERMWDS
FQNLLDYDKD EDLQRMYALL ARIPEGLEPL RKKFEEHVKR TGLAAVTKLV GEDGAGAETL
DPKNYVDALL EVHQKNSETV NRSFRGEAGF VASLDKACRE FVNRNAATGT STTKSPELLA
KHADALLRKN NKMAEEEDLE SALNKVMVLF KYIDDKDVFQ TYYTTKLSKR LIHGVSASDE
AEASMISKLK EACGFEYTNK LQRMFTDMSL SKDLTDQFKE RMQQNHDDMD INFSIMVLGT
NFWPLNAQHN EFIIPADILP VYERFSKYYQ TKHSGRKLTW LWNYSKNELR TNYLQQKYIL
MTSSWQMAVL LQYNNNDTLS LDELVAATAI NKELLKQVLA ILVKARILIN EETDQYDLNP
NFKSKKIRIN LNTPIKAEQK AESSDVLKIV DEDRKYVIQA TIVRIMKARK TMKNQALIQE
VISQISQRFA PKIPDIKKAI DHLLEKEYIE RVEGTRDTFA YVA
//
