ID M2WZF4_9PSEU Unreviewed; 379 AA.
AC M2WZF4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Rieske-type oxygenase {ECO:0000256|ARBA:ARBA00030944};
GN ORFNames=H074_29303 {ECO:0000313|EMBL:EME54126.1};
OS Amycolatopsis decaplanina DSM 44594.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1284240 {ECO:0000313|EMBL:EME54126.1, ECO:0000313|Proteomes:UP000054226};
RN [1] {ECO:0000313|EMBL:EME54126.1, ECO:0000313|Proteomes:UP000054226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44594 {ECO:0000313|EMBL:EME54126.1,
RC ECO:0000313|Proteomes:UP000054226};
RX PubMed=23558534;
RA Kaur N., Kumar S., Bala M., Raghava G.P., Mayilraj S.;
RT "Draft Genome Sequence of Amycolatopsis decaplanina Strain DSM 44594T.";
RL Genome Announc. 1:E0013813-E0013813(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EME54126.1}.
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DR EMBL; AOHO01000071; EME54126.1; -; Genomic_DNA.
DR RefSeq; WP_007033670.1; NZ_AOHO01000071.1.
DR AlphaFoldDB; M2WZF4; -.
DR PATRIC; fig|1284240.4.peg.5971; -.
DR OrthoDB; 5243643at2; -.
DR Proteomes; UP000054226; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProt.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR GO; GO:0008203; P:cholesterol metabolic process; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd03531; Rieske_RO_Alpha_KSH; 1.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR InterPro; IPR045605; KshA-like_C.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR21266:SF61; 3-KETOSTEROID-9-ALPHA-MONOOXYGENASE, OXYGENASE COMPONENT; 1.
DR PANTHER; PTHR21266; IRON-SULFUR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF19298; KshA_C; 1.
DR Pfam; PF00355; Rieske; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
FT DOMAIN 22..124
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 379 AA; 43087 MW; 7387E81F11F93CE1 CRC64;
MTTESVRQID AGAPPSRFAR GWHCLGLAEP FRDGKPHAIT AFGTKLVVFA DSSGKLNVLD
GYCRHMGGDL TQGEVKGDEI ACPFHDWRWN GNGKCVSIPY AKRVPLRART KSWLVLEENK
QLFVWHDPEG NPPPEDVVIP RIDGVFNGEW SNWTWDSVLI EGSNCREIID NMVDMAHFFY
IHYAFPTYFK NVFEGHIATQ YLNTKGRPDK GMASNYGGEE NLLRSEASYF GPSYMINKLL
NTYQGFEIEN VLINCHYPVT ENSFVLQWGV SVKKFEGVSD EHADKIAGKF AKGIGVGFLQ
DVEIWRNKTR IDNPLLCEED GPVYQLRRWY DQFYVDAADV TEDMTQRFEF EVDTSRANEV
WAAEVAENLA RQQAEEAGV
//
