ID M2XMY9_GALSU Unreviewed; 256 AA.
AC M2XMY9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=tRNA N(3)-methylcytidine methyltransferase {ECO:0000256|PIRNR:PIRNR037755};
DE EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};
GN ORFNames=Gasu_12390 {ECO:0000313|EMBL:EME31567.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME31567.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase.
CC {ECO:0000256|PIRNR:PIRNR037755}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METL family.
CC {ECO:0000256|ARBA:ARBA00009725, ECO:0000256|PIRNR:PIRNR037755}.
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DR EMBL; KB454491; EME31567.1; -; Genomic_DNA.
DR RefSeq; XP_005708087.1; XM_005708030.1.
DR AlphaFoldDB; M2XMY9; -.
DR STRING; 130081.M2XMY9; -.
DR EnsemblPlants; EME31567; EME31567; Gasu_12390.
DR GeneID; 17090203; -.
DR Gramene; EME31567; EME31567; Gasu_12390.
DR KEGG; gsl:Gasu_12390; -.
DR eggNOG; KOG2361; Eukaryota.
DR OMA; PAKYWDI; -.
DR OrthoDB; 5471626at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0001510; P:RNA methylation; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR026113; METTL2/6/8-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22809; METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR22809:SF5; TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR PIRSF; PIRSF037755; Mettl2_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|PIRNR:PIRNR037755};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR037755}.
FT DOMAIN 67..169
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
SQ SEQUENCE 256 AA; 30274 MW; D6998513B41262D8 CRC64;
MVVTSFWKEK YVVESKKNWD LFYKRNGVRF FRDRYWTLNE TSEDGFYDLL KSWTHLAESE
GRALYMLEVG CGVGNTLFPI LSLNNSIYFY ACDISEEAVR LLQDNPAFDC KRIHCFVSDV
SKEPLKNHVP LEAQLDVAIL FFSLSAMTPT QHKIVIENIC SVLRPGGWIL FRDFCKGDLA
EKRFSKENQL EDQWFVRQDG TFSYFFRIDQ VQELFESQGM NTENLKTVER RIENRKLGKK
MERRWLQDCF QKKVSV
//
