ID M2Y6W0_GALSU Unreviewed; 656 AA.
AC M2Y6W0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 39.
DE SubName: Full=ATP-dependent DNA helicase 2 subunit 2 isoform 2 {ECO:0000313|EMBL:EME31589.1};
GN ORFNames=Gasu_12600 {ECO:0000313|EMBL:EME31589.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME31589.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KB454491; EME31589.1; -; Genomic_DNA.
DR RefSeq; XP_005708109.1; XM_005708052.1.
DR AlphaFoldDB; M2Y6W0; -.
DR EnsemblPlants; EME31589; EME31589; Gasu_12600.
DR GeneID; 17090224; -.
DR Gramene; EME31589; EME31589; Gasu_12600.
DR KEGG; gsl:Gasu_12600; -.
DR OrthoDB; 5884at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR036494; Ku_C_sf.
DR InterPro; IPR014893; Ku_PK_bind.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF08785; Ku_PK_bind; 1.
DR SMART; SM00559; Ku78; 1.
DR SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EME31589.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 267..405
FT /note="Ku"
FT /evidence="ECO:0000259|SMART:SM00559"
SQ SEQUENCE 656 AA; 75792 MW; 66E1CB1AB2190AC4 CRC64;
MIEAIVLVCD IGCTLDAQSL DQLKQVSIAF FLRCLTYGSW RQLFGLVFMG SREPDNHLHN
LLGGYTHIKT VVVPERPDIS LVKYFYQCQL QGGLSDYIDA ICVSSDLLIS AVNKKKLQPR
IVLITDGKAE QFFTQQVEEI LPALKERSIR LDVIGIDDFL EDKMSHSVQI SNAALLCRLT
DSLDGTALSF KVSMEQLSEP IVKPFSLRTN YSGMLQISSV QFPVRLYTYC RDFKPPTGNR
IFWSESMESG KQVLCVKETH YFSVQEDREL EPEEMIEGHF YGRSLIPVSP FDLPALSYGA
PKCLKVLGFF AKKDFSQHIL MSGVDVMIPD PNDEISITYF VSLTEAMLEM DRVALCRYVR
RDNTSPALML MWPHLKSDGI LCLFLCQLPV LEDIRNHTFP SLHSLADNVD MEQVEAIRNW
IASRQLKDTF QSTKVFHYYH QRLLQCLQDR AIYQTLHNDE KSSLPPLSPY LERVLENTNF
LTCGRDSEST KQLWKYFPLR KVDKPKRRKQ RTMNMPSPHE ISIEPYLPPN AWSDVNESFE
EYTKEEPIEE TIFAEKSKVG EATPVADFEN MLSNKRHDWL DEAMKQMQDI IERLFSEELD
QQRDDKIIHC LTAFRKRCIM EGEELRYNRL LSDIIRKAVS ISLQLATIRS YPPLQY
//
