ID M2YJN0_PSEFD Unreviewed; 1607 AA.
AC M2YJN0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MYCFIDRAFT_216933 {ECO:0000313|EMBL:EME77960.1};
OS Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS fungus) (Mycosphaerella fijiensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=383855 {ECO:0000313|EMBL:EME77960.1, ECO:0000313|Proteomes:UP000016932};
RN [1] {ECO:0000313|EMBL:EME77960.1, ECO:0000313|Proteomes:UP000016932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRAD86 {ECO:0000313|EMBL:EME77960.1,
RC ECO:0000313|Proteomes:UP000016932};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; KB446564; EME77960.1; -; Genomic_DNA.
DR RefSeq; XP_007931695.1; XM_007933504.1.
DR STRING; 383855.M2YJN0; -.
DR GeneID; 19338334; -.
DR KEGG; pfj:MYCFIDRAFT_216933; -.
DR eggNOG; KOG0351; Eukaryota.
DR HOGENOM; CLU_001103_16_0_1; -.
DR OrthoDB; 5474026at2759; -.
DR Proteomes; UP000016932; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016932}.
FT DOMAIN 715..896
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 920..1069
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 18..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1254..1330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1504..1607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1294..1309
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1504..1538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1565..1589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1607 AA; 178723 MW; E78880E59E291B36 CRC64;
MTRNNLNEHL LWLLFDKPSL PPENLDLPPA TISFTSAVEP PPASEPDQEI TSSRGSGSRP
AGARPNPPEV VPSESHQQRS QQPREVNAAL AHVNENSDDM VRMRTAPTSA SKQHSAASVP
GHLDGTPSKN WRSASELAGA STSRGKMIGP TPMQKKLQSF DDIEEMDLTE DFASICSPPA
KRSLPDVAGK KRTSDEFELA IRSPSGSSKR PADKPRKAPR LSQEFTAIDD IVLDSPAKTG
AAPSDPPPPY STLAPLKRAT PVRQPEVPYH VAPRSAKKET FVDDSEDDDD LLNLSGHKMN
LSGKKLNPAS NVEATPSKKP SAKTRSPTKE ISMSDAAPAT KSSLQPTVRY PDLTVTPVQS
NVTTPVPPAS VLTQVIAPEM AESQAQLIQI FELPDFAYEE ALQGIEILRD AVCNEMTEAL
DEGQDDVTSF ETQLDALDSR RDALASLQTK RSTHRKLVEE KESLKQALGL AVRQRSKDLS
AHTAANKEGK ERLTRFEVDC VSLLQSCSED VKTMLSRREA RSQATKSQKV AVQSTQVPTL
RQPSDHAPAM SSSSRVVQTQ IQNFMPPPPR NNHSECSTIR HEDVYDDDLD DNDMIDADTS
HFGHRMGTPP AQYDNDDDYG MEDDEEMLDF VEGYENTSLS KAPVYRQPFA ETSGNSQMRP
PSAMKAKKAP AKKSQAEEDE LQRQKMSFRW SPDVGRVLRH VFKLKGFRKN QLEAINATLE
GQDVFVLMPT GGGKSLTYQL PALVPTGKTQ GVTIVISPLL SLMQDQVEHL RKLGVQATLI
NSETSREERD LIMDALWDRE PERMVQLLYV TPEMLGKSEK MLRTFEGLHR KRKLARIVID
EAHCVSQWGH DFRPDYKNLG EVRQRFPGVP VMALTATATE IVKSDTIHNL SMDGCAVFTS
SFNRTNLSYS VLPKPKGKQD VQSMAEVIKK DHAKDTGIIY CLSRKNCEDI AAALVNEHRI
KAKHYHAGMD SIAKADVQKE WQAGHVHVIV ATIAFGMGID KSNVRFVIHH SIPKSLEGYY
QETGRAGRDG KPSACYLYYG YGDAGKLRKM IDDGEGNWDQ KDRQHQMLSK MVQYCENKSD
CRRVQVLGYF GEAFEPEDCL GGCDNCTSGS TFEEVDYTQH ARDAISLVRE LRDQKVTILH
CIDMFRGANT KKGRDAKHEK VAHFGKGEDL DRGDVERLFY RLVNEQAIVE ESHKNKRGFV
LSYVNLGRRC NDFAPGKARL KMLIRSSPRA TKIVKKPMKR RGDDTTVKAL PMSTNVSSPV
QAVSKRKKAA AQSNVRQSRQ ANDYERDGFV VDDPSEDSFG EDAETETDDE YYAPAPQPIK
PQRKRIAPQP RGRTITIDDT MSNLSELHKD FVAQFEQEAE EKCKTLMNQN FHLKSQPFTN
TILRQMAIRW TETPEQMLRI PNIDRERVDR WGELFCKLVK KYHDHYREIM GAQAELEDDG
DDDEQPLDPN HQNVIDLVSE DEDEGGKEFE DFVDDEEEGV ESQYFSVAQY KAPDVEDFNN
RLAGMSQSAN KARAESQAAE KSTSRKGKNY SIRAANKAND ENTYRRKFSG GSRGGRYAPG
SGSGSGTGRK RTSASSKSGG ASAKNSRAPS RAQGGGFGTG SVRAMPT
//
