ID   M2Z5J1_9PSEU            Unreviewed;       315 AA.
AC   M2Z5J1;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Oxidoreductase {ECO:0000313|EMBL:EME55924.1};
GN   ORFNames=H074_24490 {ECO:0000313|EMBL:EME55924.1};
OS   Amycolatopsis decaplanina DSM 44594.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1284240 {ECO:0000313|EMBL:EME55924.1, ECO:0000313|Proteomes:UP000054226};
RN   [1] {ECO:0000313|EMBL:EME55924.1, ECO:0000313|Proteomes:UP000054226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44594 {ECO:0000313|EMBL:EME55924.1,
RC   ECO:0000313|Proteomes:UP000054226};
RX   PubMed=23558534;
RA   Kaur N., Kumar S., Bala M., Raghava G.P., Mayilraj S.;
RT   "Draft Genome Sequence of Amycolatopsis decaplanina Strain DSM 44594T.";
RL   Genome Announc. 1:E0013813-E0013813(2013).
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EME55924.1}.
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DR   EMBL; AOHO01000065; EME55924.1; -; Genomic_DNA.
DR   RefSeq; WP_007032733.1; NZ_AOHO01000065.1.
DR   AlphaFoldDB; M2Z5J1; -.
DR   PATRIC; fig|1284240.4.peg.4975; -.
DR   OrthoDB; 3727682at2; -.
DR   Proteomes; UP000054226; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05289; MDR_like_2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   4: Predicted;
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          10..295
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   315 AA;  32264 MW;  7DF14BA922C57768 CRC64;
     MKKVIFTEFG GPEVLQLVDA EDPHAGPGQV RIAVRAAGVN PVDWRIREGQ VLGAHPTVLP
     SGVGLDAAGV VDEVGEGVVG VEVGDSVFGE GSSTYAEFAV LSAWAKMPEG LTFEEAAGYP
     SVVETALRLI REVGVRPGQT LLVSGASGGV GSAVLQIARE RGIAVIGTAG AANQDYLRGL
     GALATTYGEG WVERVRRLGR VDAALDLAGS GVIAELVALT GDPGRVISIA DLGAPEFGVH
     FSGVAGSVPD ALAEAVDLIS RGRLHIPVEK SYSLTDAAAA HADSHAGHTR GRRVIVVEPV
     QAMAEGRTTT PSSSE
//