ID M3A2J5_PSEFD Unreviewed; 1181 AA.
AC M3A2J5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=DUF221-domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=MYCFIDRAFT_114224 {ECO:0000313|EMBL:EME85399.1};
OS Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS fungus) (Mycosphaerella fijiensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=383855 {ECO:0000313|EMBL:EME85399.1, ECO:0000313|Proteomes:UP000016932};
RN [1] {ECO:0000313|EMBL:EME85399.1, ECO:0000313|Proteomes:UP000016932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRAD86 {ECO:0000313|EMBL:EME85399.1,
RC ECO:0000313|Proteomes:UP000016932};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KB446556; EME85399.1; -; Genomic_DNA.
DR RefSeq; XP_007923021.1; XM_007924830.1.
DR AlphaFoldDB; M3A2J5; -.
DR GeneID; 19330246; -.
DR KEGG; pfj:MYCFIDRAFT_114224; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002458_2_0_1; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000016932; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF20; SPORULATION-SPECIFIC PROTEIN 75; 1.
DR Pfam; PF14703; PHM7_cyt; 2.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016932};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 681..706
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..755
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 775..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 850..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 883..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 919..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 188..266
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 514..623
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 637..907
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 1085..1172
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 260..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1012..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1038
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EME85399.1"
FT NON_TER 1181
FT /evidence="ECO:0000313|EMBL:EME85399.1"
SQ SEQUENCE 1181 AA; 133989 MW; DA18471110BDAF08 CRC64;
GSGQASQREG QTVNTLAASL VSAFASLGIQ VLVFMLLRLR LSRIYRPKSY LVPERERVAA
PPGGLVGWLY PLFTTTNLGL IQKCGLDAYF FLRFLRMLLK IFFPATLLAL PILLPVNHNG
GGTAKGLDKY SISNIAPKNS DRLWAHLFLG IIFILWTFYV VFKELRGYIR VRQAFLTSPQ
HRIRASATTV LVTGIPRKWL TMEALSGLYD VFPGGIRNIW INRNFDDLND KVKYRDKIAR
NLEDAETVLI KNCRKKHIEA EQKKAKEDGK KKSKKEKLQD EAEEDAAAER MAQSEGVSAG
ENHELSQDLK DTLKEEEQHQ ADSDKRRRNP LGLVGDSVNA VGHGFKDVGK GISKFGDRVV
GGVDNGFHKA GDDLNIATRR ANAGGGFSLD DDLTLDVRDV HTTRPAGDTR PKSSLQIEEP
AHHKGNRKSW NIFKNNDESL AMHSPQPHTA EDDDEFPLHG DAEQKEPEAK DKQKSKSFMQ
KLAFWKKNND EEDEDKDEYP NAIDKKWDED QDEEPYWRRY LEPKDRETIR LPLFCPTWFP
SIPLIGKKVD RIYHLRRELA RLNLEIEEDQ KDIEKFPYMN SAFIQFNHQV AAHMCCQSLS
HHIPQHMAPR LVEISPEDVI WDNMSVKWWE RYLRTGLILL ISAGLILLFA IPVAFTSLLN
KVSQLASYIS WLEWLTTLPD VVISIIQGVL PPVLLSLILL LVPIIFRLLI KQQGVPTGND
RERGVQSWYF AFLFIQVFLV VTISGGLIAI FQALADNPTS IVTEVASNIP TASNYFFSYL
TVQALSNSAS ALLQLGSLFG WFILAPILDS TARQKWTRQT SLQYVTWGTF FPPFTNFAVI
GIIYSIVSPL ILVFMIFIFA LFWIVYRYNV LFVYQFKHDT GGLLFPVAIN QLFTGIYFLE
IAMIGYFFTL QYKGEVVCLP QAIIMIVMLV LTVVFQWLTN MSFKPLFQYL PITLEDEAVI
RDEQFAKAQE SKFAPLNESG NDERDVQDML EDREHAEEDA DRAAIDEEKR AIAQRRSHTP
GSTHSPDARR TSGSAHSARP GSHWAKKSEA KPVWGTELWK KAAPEAKTDA EAQHTVGDVL
FSGYADELED LTPDERDLLV RYAFQHSALR ARRPVVWIPR DQLGVSDDEI KRAKKMSTVS
IDGQNRTNIW MSNEGTALDG KGRVVFRRSP PDFSNVDLIA L
//
