ID M3CMG0_SPHMS Unreviewed; 355 AA.
AC M3CMG0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=NAD_binding_2-domain-containing protein {ECO:0000313|EMBL:EMF14988.1};
GN ORFNames=SEPMUDRAFT_146990 {ECO:0000313|EMBL:EMF14988.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF14988.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF14988.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF14988.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB456261; EMF14988.1; -; Genomic_DNA.
DR RefSeq; XP_016763109.1; XM_016904010.1.
DR AlphaFoldDB; M3CMG0; -.
DR STRING; 692275.M3CMG0; -.
DR GeneID; 27901147; -.
DR eggNOG; KOG0409; Eukaryota.
DR HOGENOM; CLU_035117_6_1_1; -.
DR OMA; NNMMLFI; -.
DR OrthoDB; 203032at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR22981:SF81; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016931}.
FT DOMAIN 7..155
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 183..308
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
SQ SEQUENCE 355 AA; 38670 MW; CDCEC0EA8EB3E0FE CRC64;
MADLPKTIGW IGLGLMGYPM ARNLVKKMSS DTHFHVYDVV QENVDKFVND GEGRAHACTS
CKEVADKDLI LSMVPEGAHV KRVYLDPETG VLLSSLNTKI LIDCSTIDTA SSLAVREATL
STHPQATFYD APVSGGVLGA EKGTLTFMLG CSQSDPHLPL LDALFRLMGN PSAIFPAGGP
SLGLTAKLCN NYCSGLIAIA VSEAMNIGIR SGMDPRILAN IFHTSTAQSA ICDDWNPVPG
LCPTAPASQN YQGGFRVQLM KKDFGLAVEI AEHVGATLAL GGLGLKVYEE ASRDERYRDL
DSRVVYRYLD GVEKWNEEGK FEERVEMKRD ETRRLLKVAR EVGERGTVEK ARNIM
//
