ID   M3DM98_LEPIR            Unreviewed;       603 AA.
AC   M3DM98;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=GHKL domain protein {ECO:0000313|EMBL:EMF42343.1};
GN   ORFNames=LEP1GSC067_0473 {ECO:0000313|EMBL:EMF42343.1};
OS   Leptospira interrogans serovar Lora str. TE 1992.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1193028 {ECO:0000313|EMBL:EMF42343.1, ECO:0000313|Proteomes:UP000011754};
RN   [1] {ECO:0000313|EMBL:EMF42343.1, ECO:0000313|Proteomes:UP000011754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TE 1992 {ECO:0000313|EMBL:EMF42343.1,
RC   ECO:0000313|Proteomes:UP000011754};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Hartskeerl R.A., Ahmed A.,
RA   van der Linden H., Goris M.G.A., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA   Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000256|ARBA:ARBA00008239}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMF42343.1}.
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DR   EMBL; AKWW02000041; EMF42343.1; -; Genomic_DNA.
DR   AlphaFoldDB; M3DM98; -.
DR   Proteomes; UP000011754; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 3.30.230.80; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   PANTHER; PTHR11528:SF26; HEAT SHOCK PROTEIN (HSP90 FAMILY)-RELATED; 1.
DR   PANTHER; PTHR11528; HEAT SHOCK PROTEIN 90 FAMILY MEMBER; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
SQ   SEQUENCE   603 AA;  68553 MW;  A01B0A2EDAD663F2 CRC64;
     MSHKFQVNLR GIINLLSEHL YSGPQVFVRE LLQNGVDAIQ ARSYLEPENE GEIHLEIIPG
     KDGTPPTLIF TDNGVGLVES EIHEFLATIG QSSKRGEFQS PKGFIGQFGV GLLSCFIVSD
     EVVVVTRSVK DKTQPAFEWR GKQDGTYSIK TLGSDLPFGT QVYLLCKPGS EEYFERETLC
     NLVKKFGGLL SVPLQFLEGE STELLNPEPA PWNRTYRSKA QERKTFLDFG KKLFETSFFD
     AIPLTSDIGK VQGIAFVLPY SPSLAQKNIH RIYLKNMLLS ESAASLLPDW AFFVKCVVNS
     DELRPTASRE DFYEDQSLEK ARETLGQCLR DYLIALSEDE PERLRHLINL HHLSMKALAV
     QDSDFFRLII DFLPFETTFG RMTLKEFREK NPVIRYVSSH DQYRQISGVA AAQGEAIING
     GYVYDSELLE RFSELYPVEQ VDAAGFAQTF EDITLEERDS VFDFLQVADQ VLRPFQCVTD
     IKKFLPIEMP MLYHLSQEGD FLRSVEHSKE IANKMWSDIL NNLSDSYSKE INAYLFFNLR
     NPLIQKLVKL KDVQLIGRAV QMLYIQALLM GHHPLHVKEL SLLTGGLSDL IEGCINNQIR
     ENQ
//