ID   M3G7F2_LEPIT            Unreviewed;       580 AA.
AC   M3G7F2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Peptidase, M61 glycyl aminopeptidase family protein {ECO:0000313|EMBL:EMG21205.1};
DE            EC=3.4.11.- {ECO:0000313|EMBL:EMG21205.1};
GN   ORFNames=LEP1GSC150_1246 {ECO:0000313|EMBL:EMG21205.1};
OS   Leptospira interrogans serovar Copenhageni str. LT2050.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1001598 {ECO:0000313|EMBL:EMG21205.1, ECO:0000313|Proteomes:UP000011778};
RN   [1] {ECO:0000313|EMBL:EMG21205.1, ECO:0000313|Proteomes:UP000011778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2050 {ECO:0000313|EMBL:EMG21205.1,
RC   ECO:0000313|Proteomes:UP000011778};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Tulsiani S.M., Graham G.C., Burns M.-A.,
RA   Dohnt M.F., Smythe L.D., McKay D.B., Craig S.B., Vinetz J.M., Sutton G.G.,
RA   Nierman W.C., Fouts D.E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMG21205.1}.
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DR   EMBL; AFMD02000339; EMG21205.1; -; Genomic_DNA.
DR   AlphaFoldDB; M3G7F2; -.
DR   Proteomes; UP000011778; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 2.60.40.3650; -; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR024191; Peptidase_M61.
DR   InterPro; IPR007963; Peptidase_M61_catalytic.
DR   InterPro; IPR040756; Peptidase_M61_N.
DR   Pfam; PF05299; Peptidase_M61; 1.
DR   Pfam; PF17899; Peptidase_M61_N; 1.
DR   PIRSF; PIRSF016493; Glycyl_aminpptds; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:EMG21205.1};
KW   Hydrolase {ECO:0000313|EMBL:EMG21205.1};
KW   Protease {ECO:0000313|EMBL:EMG21205.1}.
FT   DOMAIN          11..169
FT                   /note="Peptidase M61 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17899"
FT   DOMAIN          259..376
FT                   /note="Peptidase M61 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF05299"
SQ   SEQUENCE   580 AA;  66785 MW;  C4980A1E9A4A895E CRC64;
     MYKLHFVIQE YQLTGHYLQV ELEVESSQNE TVFCLPVWSP GSYMVRDYSR HIHKLEASTF
     GKNGKNLEIS QIGLDSWKIQ NEGKSFHLRY VVYGYDYSVR SNYFTTEFCI LHPPALFLYP
     KDQVVSEITL EISNDLPFDF CHSGLNGKGK KRFSKNLDEF LDTPILLSNR EEISFQSGGC
     DHEIVFEGEL PKSIQKTLIS DLQKITAEQI RCMGVSPNTR YLFILILSEG AYGGLEHLNS
     SVNMYDPLKA VSKDGYLKLL ELLSHEYFHL WNVKRIRPIA LGPFDYQKPS LTKELWIAEG
     ITSFYDAYFL VKTKHLNPES YLVKVMEDLQ SLEKSEGESW MSLEDSSFTA WTKFYNRPND
     PNANNTGISY YVKGGILALA MNLHLLSETF GKHSLLDVMN EVYQSFHIGK NRGFTKIEFF
     EAAKKRTGID LKLEFGDYLD KPVSIPIEKY LHKIGVKRLD SNPGIELGFG TRDERGYLFI
     NKIDWKFLDT SVDLSLGDEW IALNGIRIHS GNRKDLLKQC KAGEKIELLI SRRGKILKRK
     MKLSKRFQTS QLKLEDHLSE EQTKLRNLFF GLDKSSSSKS
//