ID M3GCB2_LEPBO Unreviewed; 602 AA.
AC M3GCB2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EMF98541.1};
GN ORFNames=LEP1GSC123_4405 {ECO:0000313|EMBL:EMF98541.1};
OS Leptospira borgpetersenii str. 200701203.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1193007 {ECO:0000313|EMBL:EMF98541.1, ECO:0000313|Proteomes:UP000011783};
RN [1] {ECO:0000313|EMBL:EMF98541.1, ECO:0000313|Proteomes:UP000011783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=200701203 {ECO:0000313|EMBL:EMF98541.1,
RC ECO:0000313|Proteomes:UP000011783};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Picardeau M., Werts C., Goarant C.,
RA Vinetz J.M., Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMF98541.1}.
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DR EMBL; AKWO02000085; EMF98541.1; -; Genomic_DNA.
DR AlphaFoldDB; M3GCB2; -.
DR BioCyc; LBOR1193007:G11KN-4033-MONOMER; -.
DR Proteomes; UP000011783; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000011783};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 545..602
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 602 AA; 67080 MW; 7867C6D6FE1B4A4B CRC64;
MKSHKTRLTI LFSFLCILFC ILIGRVVFLT FWNEREVVLK TGDRIMRGAI YDRRGIELAM
TVDSATIGIY PANIYDPNFT AVQLAPYLDM PPEKIEAIIR EKSRYFLLKR EIDESLGNKI
MELSLPGVRR EKEYKRVYPH GNLASSLVGF TGMDDDRALS GLEVQYNQEL MTPTESDSSR
GSNLHLTIDG LIQYKLEKAL GKRFEETGSK KAIGILMDIN TGKILASASF PAFDPNQYNE
SGEDSHTNWA IRHVYEPGST MKIFLASVLF NENLIRPDEK FHCPGYVELG KTKIKCTNAH
GHLNLEEILQ YSCNVGIIKA SQRIPEALLY DYMKKFQFGE KTGFLPNESA GYFPPLKKWT
PATSMFMAIG QGISVTPIQL VASAASVANG GRMLTPRVVS HFSDSYGAIL HEFKTQETPI
GIREYTTEKI LKAMTRVVQS GTGKNAYIQE YSIAGKTGTG QKAISGKGYV EGLWSASFLG
FFPAERPKIV GLILFDEPKG GTHSGGGLAA PVFKEVVENI IPIIEQGERT LNVSLKHFQR
KNLKGTNVGE IPNLIGKSKR EALEILRPSG IPIKFHGSGF CYKQEPDPGK KTEDGRLNLY
FK
//
