ID M3HDV7_CANMX Unreviewed; 1301 AA.
AC M3HDV7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Fatty acid synthase beta subunit dehydratase {ECO:0000313|EMBL:EMG45417.1};
DE Flags: Fragment;
GN ORFNames=G210_4400 {ECO:0000313|EMBL:EMG45417.1};
OS Candida maltosa (strain Xu316) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=1245528 {ECO:0000313|EMBL:EMG45417.1, ECO:0000313|Proteomes:UP000011777};
RN [1] {ECO:0000313|EMBL:EMG45417.1, ECO:0000313|Proteomes:UP000011777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xu316 {ECO:0000313|Proteomes:UP000011777};
RA Yu J., Wang Q., Geng X., Bao W., He P., Cai J.;
RT "Genome sequence of Candida maltosa Xu316, a potential industrial strain
RT for xylitol and ethanol production.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMG45417.1}.
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DR EMBL; AOGT01002478; EMG45417.1; -; Genomic_DNA.
DR STRING; 1245528.M3HDV7; -.
DR eggNOG; ENOG502QQJX; Eukaryota.
DR HOGENOM; CLU_000114_5_1_1; -.
DR OMA; HDGHIAR; -.
DR OrthoDB; 5488314at2759; -.
DR Proteomes; UP000011777; Unassembled WGS sequence.
DR GO; GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
DR GO; GO:0004317; F:(3R)-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; IEA:InterPro.
DR GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:InterPro.
DR GO; GO:0004312; F:fatty acid synthase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd03447; FAS_MaoC; 1.
DR Gene3D; 1.20.930.70; -; 1.
DR Gene3D; 3.30.1120.100; -; 1.
DR Gene3D; 3.30.70.3330; -; 1.
DR Gene3D; 6.10.140.1400; -; 1.
DR Gene3D; 6.10.60.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 2.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013565; Fas1/AflB-like_central.
DR InterPro; IPR040883; FAS_meander.
DR InterPro; IPR003965; Fatty_acid_synthase.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR039569; MaoC-like_dehydrat_N.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR10982:SF21; FATTY ACID SYNTHASE SUBUNIT BETA; 1.
DR PANTHER; PTHR10982; MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF08354; Fas1-AflB-like_hel; 1.
DR Pfam; PF17951; FAS_meander; 1.
DR Pfam; PF13452; MaoC_dehydrat_N; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR PRINTS; PR01483; FASYNTHASE.
DR SMART; SM00827; PKS_AT; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 4: Predicted;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000011777}.
FT DOMAIN 916..1270
FT /note="Malonyl-CoA:ACP transacylase (MAT)"
FT /evidence="ECO:0000259|SMART:SM00827"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMG45417.1"
SQ SEQUENCE 1301 AA; 146453 MW; 9A885DAB9FF7F2C0 CRC64;
MYSKIRRCSN IILVAGSGFG SDEDTYPYLT GLWSKKFNYP PMPFDGVLFG SRVMTAKEAH
TSLEAKKLIA QCPGVPDEKW EQTYKKPTGG IITVRSEMGE PIHKIATRGV MFWKELDETI
FNLPKNKLLE GLNKKRDYII KKLNNDFQKP WFAKNANGVC DLQEMTYEEI ANRLVELMYV
KKSQRWIDVS LRNLYGDYLR RVEERFTSQT GVVSLLQNFG QLSEPEKFTA EFFKKFPAAK
QQLISQEDAD HFLLLAARPA QKPVPFVPVL DERFEFFFKK DSLWQSEDLE SVVGEDVQRT
CILHGPVASQ FTNKVDEPIG EILDSIHDGH IARLIKDEYA GDESKIPVVE YFGGYNAREV
AVAAENVEIT DSKQEVVYEI GTKLPAKQDW LDLLAGTELN WLHALLATDR IVQGTRHVAN
SLHDILTPVP HSKVVINKST QKLTAYEKVK GELLPVAEIE LIKPNTIQLS LIEHRTADGK
PVALPFLYNY NPADGFAPIL EVMGDRNDRI KEFYWKLWFG SSVPYDNEIN VEEQILGEEI
TISSQDISEF THAIGNKCEA FVNRPGKVTL APMDFAIVIG WKAIIKAIFP KTVDGDLLKL
VHLSNGYKMI TGAKPLQKDD VVSTKAEIRA VLNQPSGKLV EVVGTIYREG KPVMEVTSQF
LYRGEYNDYN NTFQKVTETP YKVAFNAPKD LAVLRSKEWF HLEKDVEFDA LTFRCESTYK
FKSANVYSSI RTTGQVLLEL PTQEVIQIGT VDYEAGTSYG NPVTDYLSRN GKTIEEAVTF
ENAIPLSSGE ELTSKAPGTN EPYAIVSGDY NPIHVSRVFA AYAKLPGTIT HGMYSSASIR
GLVEEWAANN VAARVRAFKC DFVGMVLPND TLQTTMEHVG MINGRKIIKV ETRNVETEVP
VLIAEAEIEQ PTTTYVFTGQ GSQEQGMGMD LYNSSEVARA VWDKADKHFI NNYGFSILDI
VQNNPKEMTI HFGGAKGRAI RDNYITMMFE TIGEDGSLKS EKIFKDIDET TTSYTFVSDT
GLLSATQFTQ PALTLMEKAA YEDIKSKGLI PTDIMFAGHS LGEYSALSSL ANVMPIESLV
DVVFYRGMTM QVAVARDEYG RSNYGMVAVN PTRVSPTFND AALRFVVDEV SNKTTWLLEI
VNYNVENQQY VAAGDLRALD TLTNVLNVLK INKIDIVKLQ EQLSIEKVKE HLYEIIDEVA
AKSLAKPQPI DLERGFAVIP LKGISVPFHS SYLMSGVKPF KRFLCKKIPK SSVKPQDLIG
KYIPNLTAKP FELTKEYFQD VYDLTKSEKI KNILDNWEKY E
//
