ID M3X477_FELCA Unreviewed; 474 AA.
AC M3X477;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Methyltransferase like 25B {ECO:0000313|Ensembl:ENSFCAP00000021427.1};
GN Name=METTL25B {ECO:0000313|Ensembl:ENSFCAP00000021427.1,
GN ECO:0000313|VGNC:VGNC:64777};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000021427.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000021427.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000021427.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000021427.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000021427.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000021427.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000021427.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04002876; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003999667.1; XM_003999618.4.
DR AlphaFoldDB; M3X477; -.
DR STRING; 9685.ENSFCAP00000021427; -.
DR PaxDb; 9685-ENSFCAP00000021427; -.
DR Ensembl; ENSFCAT00000023606.4; ENSFCAP00000021427.1; ENSFCAG00000025578.4.
DR GeneID; 101082289; -.
DR KEGG; fca:101082289; -.
DR CTD; 51093; -.
DR VGNC; VGNC:64777; METTL25B.
DR eggNOG; KOG2651; Eukaryota.
DR GeneTree; ENSGT00530000063745; -.
DR HOGENOM; CLU_016581_3_0_1; -.
DR InParanoid; M3X477; -.
DR OMA; QQARKWD; -.
DR OrthoDB; 3060170at2759; -.
DR Proteomes; UP000011712; Chromosome F1.
DR Bgee; ENSFCAG00000025578; Expressed in uterus and 10 other cell types or tissues.
DR GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12496:SF2; METHYLTRANSFERASE-LIKE PROTEIN 25B; 1.
DR Pfam; PF13679; Methyltransf_32; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01131; RRNA_A_DIMETH; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 133..291
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13679"
SQ SEQUENCE 474 AA; 52824 MW; 8C9DA78A1D9BB96B CRC64;
MPGVSARGLS HEERRQLAVN LTRVLARYRP ILDAYIIEFF TDNLWGTLPC SWQEALDGLN
PPQLAAQLLG MPGEGEVVRY RSVWPLTLLA LKSTAYALAF TRTPGFQTPS EFLENPSQSS
RLTAPFRKHV RPKKQHEIRR LGELVKKLSD LTGCTQVVDI GSGQGHLSRF MSLGLGLTVK
SIEGDRRLVE RAQRLDRELL QALEKEEKRS PQVTRAGPRH SPHHVVRWVE PTALCEELLL
PLEPLPPRGA RLLLTGLHAC GDLSVALLRH FSCPEVVALA SVGCCYMKLS EPGGYPLSQW
VAGLRGSELP YRLREGACHA LEDYAERLQR AGPGLRTHCY RAALETVIRG ARPELRRPGV
QGIPRVHELK IEEYVQRGLR RVGLDPQLPL NLAALRAHQA QENRVVAFFS LALLLAPLVE
TLILLDRLLC LQEQGFHAEL LPIFSPELSP RNLVLVATKS PLGEAFSLLE TEDS
//
