ID M3XCF0_FELCA Unreviewed; 352 AA.
AC M3XCF0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Cytoplasmic dynein 2 light intermediate chain 1 {ECO:0000256|ARBA:ARBA00018863};
GN Name=DYNC2LI1 {ECO:0000313|Ensembl:ENSFCAP00000024304.2,
GN ECO:0000313|VGNC:VGNC:61681};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000024304.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000024304.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024304.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000024304.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024304.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000024304.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024304.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton, cilium
CC axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton,
CC cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
CC -!- SIMILARITY: Belongs to the dynein light intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00006831}.
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DR EMBL; AANG04002548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XCF0; -.
DR STRING; 9685.ENSFCAP00000024304; -.
DR PaxDb; 9685-ENSFCAP00000024304; -.
DR Ensembl; ENSFCAT00000025973.4; ENSFCAP00000024304.2; ENSFCAG00000024777.4.
DR VGNC; VGNC:61681; DYNC2LI1.
DR eggNOG; KOG3929; Eukaryota.
DR GeneTree; ENSGT00390000010498; -.
DR HOGENOM; CLU_049395_0_0_1; -.
DR InParanoid; M3XCF0; -.
DR OMA; FWEIAQG; -.
DR Proteomes; UP000011712; Chromosome A3.
DR Bgee; ENSFCAG00000024777; Expressed in testis and 10 other cell types or tissues.
DR GO; GO:0045177; C:apical part of cell; IEA:Ensembl.
DR GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR GO; GO:0035869; C:ciliary transition zone; IEA:Ensembl.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:Ensembl.
DR GO; GO:0045504; F:dynein heavy chain binding; IBA:GO_Central.
DR GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR GO; GO:0035721; P:intraciliary retrograde transport; IBA:GO_Central.
DR GO; GO:0035735; P:intraciliary transport involved in cilium assembly; IBA:GO_Central.
DR GO; GO:1902017; P:regulation of cilium assembly; IEA:Ensembl.
DR InterPro; IPR040045; DYNC2LI1.
DR InterPro; IPR022780; Dynein_light_int_chain.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13236:SF0; CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1; 1.
DR PANTHER; PTHR13236; DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2; 1.
DR Pfam; PF05783; DLIC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT REGION 303..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 39888 MW; 692F45EF50BC0C3B CRC64;
MPSETLWEIA KAEVEKRGSG GGEGDGVEIG EKSVFFIGSK NGGKTTIILR CLDRDEPPKP
TLALEYTYGR RTKGHNIPKD IAHFWELGGG TSLLDLISIP ITSDTLRTFS IVLVLDLSKP
NDLWPTMENL LQAMKNHVDK MIMKLGKTNS KAASEMRQRI WSNMQKDHPQ DRELVDPFLI
PLVIIGSKYD IFQDFDSEKR KVICKTLRFV AHYYGASLMF TSKSEALLLK IRGVINQLAF
GIDRSKSICV DQNKPLFITA GLDSLSQIGS PPVPDNDIGK LHARSPMELW KKVYERVFPP
KSINTLKDTK DPAKDPQYAE REVDEMRMQK DQELEQYKRS SSKSWKQIEL DS
//
