ID M3XCT1_FELCA Unreviewed; 250 AA.
AC M3XCT1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE SubName: Full=Chromobox 7 {ECO:0000313|Ensembl:ENSFCAP00000024437.1};
GN Name=CBX7 {ECO:0000313|Ensembl:ENSFCAP00000024437.1,
GN ECO:0000313|VGNC:VGNC:60425};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000024437.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000024437.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024437.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000024437.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024437.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000024437.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024437.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04001989; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003989318.1; XM_003989269.3.
DR AlphaFoldDB; M3XCT1; -.
DR STRING; 9685.ENSFCAP00000024437; -.
DR PaxDb; 9685-ENSFCAP00000024437; -.
DR Ensembl; ENSFCAT00000023983.4; ENSFCAP00000024437.1; ENSFCAG00000026160.4.
DR GeneID; 101082836; -.
DR KEGG; fca:101082836; -.
DR CTD; 23492; -.
DR VGNC; VGNC:60425; CBX7.
DR eggNOG; KOG2748; Eukaryota.
DR GeneTree; ENSGT00940000158365; -.
DR HOGENOM; CLU_042051_1_0_1; -.
DR InParanoid; M3XCT1; -.
DR OMA; KPHKAHK; -.
DR OrthoDB; 75895at2759; -.
DR Proteomes; UP000011712; Chromosome B4.
DR Bgee; ENSFCAG00000026160; Expressed in prefrontal cortex and 10 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0031519; C:PcG protein complex; IBA:GO_Central.
DR GO; GO:0035102; C:PRC1 complex; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd18646; CD_Cbx7; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR043000; CBX7.
DR InterPro; IPR033773; CBX7_C.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR017984; Chromo_dom_subgr.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR PANTHER; PTHR47277; CHROMOBOX PROTEIN HOMOLOG 7; 1.
DR PANTHER; PTHR47277:SF1; CHROMOBOX PROTEIN HOMOLOG 7; 1.
DR Pfam; PF17218; CBX7_C; 1.
DR Pfam; PF00385; Chromo; 1.
DR PRINTS; PR00504; CHROMODOMAIN.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS00598; CHROMO_1; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 11..69
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 148..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 250 AA; 28320 MW; 157F69F0D65A0003 CRC64;
MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK
EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTRPLG SGSPEGVVKA
GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PDLESHSHPR ELFLQEPAAP
DVLQAASEWE PAEQPPEEED ADLAEGPPPW TPVLPPSEVT VTDITANSVT VTFREAQAAE
GFFRDRGGKF
//
